Relationship of Staphylococcal Colonization to Infection

MRSA Infection Clinical Trial

Official title:

Relationship of Staphylococcal Colonization to Infection

Clinical Trial Details — Status: Withdrawn

Administrative data

• NCT number: NCT00766259
• Other study ID #: Eng-MRSA
• Status: Withdrawn
• Start date: July 2009
• Est. completion date: June 2012

Study information

• Verified date: March 2021
• Source: Veterans BioMedical Research Institute
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Inpatients will be prospectively have nares screened and MRSA strains collected. All clinical MRSA strains of patients will also be prospectively collected. A sensitive strain discrimination test of spa typing will be used to determine if the strains are related. Hypotheses are

1. Strain colonization durations vary and may be very short in days to weeks.

2. Colonizing strains rarely infect 3) Both 1 and 2 may be affected by the patient's co-morbidity.

Description:

Patients of special interest:

1. Skin and soft tissue infection

2. Nursing home patients

3. Vascular patients with leg lesions

4. ICU patients

5. Hemodialysis patients

6. Outpatients without history of infections(controls) will have nares screened for MRSA and then monthly for 1 year.

All strains will be saved and spa typed. Analysis of the data will be performed to answer the questions and hypotheses and to answer is the screening effort and the isolation of patients for MRSA as is in current practice worthwhile and is there any scientific data to support this practice

Recruitment information / eligibility

• Status: Withdrawn
• Enrollment: 0
• Est. completion date: June 2012
• Est. primary completion date: June 2011
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• Admitted and one of the co-morbid groups

• Ambulatory care patient with no infections

Exclusion Criteria:

• All others

Related Conditions & MeSH terms

• Communicable Diseases
• Infections
• MRSA Infection

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Veterans BioMedical Research Institute

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Percent of infection strains which were also colonizer earlier		3 years
Secondary	Duration of strain colonization among co-morbidity cohorts		3 years