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MRSA Infection clinical trials

View clinical trials related to MRSA Infection.

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NCT ID: NCT01814371 Completed - Clinical trials for Staphylococcus Aureus

Individualized vs. Household MRSA Decolonization

HOME2DS
Start date: April 2013
Phase: N/A
Study type: Interventional

The purpose of this research study is to compare the effectiveness of commonly used decolonization treatments (application of mupirocin antibiotic ointment to the nose and bleach baths) when performed by individuals with a history of skin and soft tissue infection (SSTI) in the prior year (individualized approach) in comparison to decolonization of all household members (household approach) in an attempt to prevent Staphylococcus aureus skin infections. The investigators hypothesize an individualized decolonization approach will be equally as effective as a household approach to prevent SSTI.

NCT ID: NCT01724671 Not yet recruiting - Pneumonia Clinical Trials

Vancomycin Versus Ceftaroline in Patients With Infections Caused by MRSA That Are Susceptible to Ceftaroline

Start date: December 2012
Phase: N/A
Study type: Observational

To compare the time to pathogen eradication, and the relationship to the time to clinical improvement, between ceftaroline and case-matched vancomycin treated controls in the treatment of adults with serious infections caused by Methicillin-Resistant Staphylococcus aureus (MRSA).

NCT ID: NCT00790972 Withdrawn - MRSA Infection Clinical Trials

The Efficacy of SinoFresh Nasal and Sinus Care Nasal Spray in Eliminating MRSA From the Nasal Cavity

Start date: June 2007
Phase: N/A
Study type: Interventional

This is a study to assess the ability of SinoFresh Nasal & Sinus Care, an FDA approved over-the-counter nasal spray, to eliminate the bacteria in your nose.

NCT ID: NCT00766259 Withdrawn - MRSA Infection Clinical Trials

Relationship of Staphylococcal Colonization to Infection

Start date: July 2009
Phase:
Study type: Observational

Inpatients will be prospectively have nares screened and MRSA strains collected. All clinical MRSA strains of patients will also be prospectively collected. A sensitive strain discrimination test of spa typing will be used to determine if the strains are related. Hypotheses are 1. Strain colonization durations vary and may be very short in days to weeks. 2. Colonizing strains rarely infect 3) Both 1 and 2 may be affected by the patient's co-morbidity.

NCT ID: NCT00731783 Completed - Clinical trials for Staphylococcus Aureus

Staphylococcus Aureus Decolonization Study

SuDS
Start date: July 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether measures to eliminate the Staph germ from the skin of the index patient (with a special ointment and soap) are more effective when performed by everyone in the household rather than the patient alone, and whether these methods are effective in preventing future Staph infections. The investigators hypothesize that there will be a greater number of households who are successful in eradicating the staph germ from the index patient when all members of the household participate than households where only the index patient is treated.

NCT ID: NCT00711854 Completed - MRSA Infection Clinical Trials

Randomized Clinical Trial to Compare a Regimen of Trimethoprim-sulfamethoxazole Plus Rifampicin With a Regimen of Linezolid in the Treatment of Methicillin-Resistant Staphylococcus Aureus (MRSA) Infection

Start date: January 2009
Phase: Phase 4
Study type: Interventional

MRSA infections often require systemic antibiotic therapy and represent an important healthcare burden. Currently available treatment options are either only available in parenteral form (vancomycin) or expensive (linezolid). Thus, there is an urgent, unmet need to better investigate in-expensive but highly active alternatives to currently recommended standard treatment options. The purpose of the proposed study is to test the hypothesis that a combination of TMP-SMX and rifampicin is not inferior to linezolid for treatment of MRSA infections.

NCT ID: NCT00685867 Completed - MRSA Infection Clinical Trials

Two Strategies for Methicillin-resistant Staphylococcus Aureus (MRSA) Infection Prevention in Surgical Patients

MOSAR-04
Start date: May 2008
Phase: N/A
Study type: Interventional

The study is a two-arm controlled multi-centre trial of two strategies to reduce nosocomial MRSA transmission and infection among surgical patients. Enrolment and primary analyses will be performed at the hospital level. A total of ten adult surgical departments with at least 3 surgical subspecialties each will participate in the study. Sites of the study are located in 9 countries (UK, France, Spain, Germany, Switzerland, Italy, Serbia, Greece and Israel). The primary objective is to determine the effect of an early MRSA detection & decolonization & isolation strategy compared to an enhanced standard control strategy on healthcare-associated MRSA isolation rates among surgical patients at risk of MRSA carriage, who are hospitalized for at least 24 hours.

NCT ID: NCT00502476 Recruiting - MRSA Colonization Clinical Trials

Multicenter Trial of Daily Chlorhexidine Bathing to Reduce Nosocomial Infections

CBET
Start date: August 2007
Phase: N/A
Study type: Observational

To determine if daily bathing with chlorhexidine impregnated washcloths will reduce the incidence of MRSA and VRE within an Intensive Care Unit (ICU) or ward setting.

NCT ID: NCT00448942 Completed - MRSA Colonization Clinical Trials

The Impact of Chlorhexidine-Based Bathing on Nosocomial Infections

Start date: November 2004
Phase: N/A
Study type: Observational

The purpose of this study was to determine if the use of daily chlorhexidine bathing would decrease the incidence of MRSA and VRE colonization and healthcare associated Bloodstream Infections (BSI) among Intensive Care Unit (ICU) patients.