Acute Effect of Resistance Exercise, Neuromuscular Electrical Stimulation, and Transcutaneous Electrical Stimulation Applications on Muscle Activation

Motor Activity Clinical Trial

Official title:

Acute Effect of Resistance Exercise, Neuromuscular Electrical Stimulation, and Transcutaneous Electrical Stimulation Applications on Muscle Activation

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06016660
• Other study ID #: EMGHealthy
• Status: Completed
• Phase: N/A
• Start date: May 1, 2022
• Est. completion date: January 1, 2023

Study information

• Verified date: August 2023
• Source: Gazi University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of our study is to investigate the effects of single-session resistance exercise, neuromuscular electrical stimulation, and transcutaneous electrical stimulation on the level of muscle activation and their superiority over each other on both the ipsilateral and contralateral sides. Our randomized controlled crossover study included 21 participants (13 female, 8 male, age; 27.7±4). Transcutaneous electrical stimulation was used for sensory input. A single-session application was performed only to the right extremities of all participants, and the acute effects on muscle activation on both the ipsilateral and contralateral sides were evaluated. Muscle activation was evaluated with superficial EMG. SPSS® Statistics V22.0 software was used for statistical analysis. As a result of the statistical analysis, a significant increase in activation was found only in the sensory input application group on the ipsilateral side flexor carpi radialis (FCR) (p=0.001), flexor carpi ulnaris (FCU) (p<0.001), flexor digitorum superficialis (FDS) (p=0.023) and flexor digitorum profundus (FDP) (p=0.003) muscles. On the contralateral side, there was an increase in activation in all muscles (FCR; p<0.001, FCU; p=0.033, FDS; p=0.017 and FDP; p=0.001) in the resistant exercise group. In addition, there was a significant increase in the activation of certain muscles on the contralateral side in the NMES application group (FCR (p=0.049) and FDP (p=0.016) muscles) and the sensory input application group (FDP (p=0.004) and FDS (p=0.043) muscles). In situations where movement is contraindicated, ipsilateral sensory input can increase the level of muscle activation through both cortical and peripheral neural mechanisms.In addition, resistance exercise to be performed on the contralateral side can be an effective application to increase muscle activation on the ipsilateral side.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 21
• Est. completion date: January 1, 2023
• Est. primary completion date: October 1, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• After providing detailed information about the study, individuals who had agreed to participate in the research were included in the study.

Exclusion Criteria:

• Individuals with any central or peripheral nervous system disease/injury affecting the upper extremity,
• Individuals with a history of orthopedic injury that could impact the study,
• Individuals with a history of neuromuscular disease, congenital anomalies, skin infections, or cognitive impairments,
• Individuals with a history of systemic or metabolic diseases that could potentially affect the study,
• Individuals with a body mass index (BMI) above 30 kg/m2.

Related Conditions & MeSH terms

• Motor Activity

Intervention

Other:
• Physiotherapy
Resistance exercise, Neuromuscular electrical stimulation, and Transcutaneous electrical stimulation

Locations

Country	Name	City	State
Turkey	Baris SEVEN	Izmir	Çigli

Sponsors (1)

Lead Sponsor	Collaborator
Gazi University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Superficial electromyography	Muscle activation measurement	through study completion, an average of 1 year