Motivation Clinical Trial
Official title:
The Influence of Mesolimbic-hippocampal Interactions on Episodic Memory During Active Information Seeking
Study 1 will use a novel Game Show task, in which the investigators manipulate participant's agency to control their learning environment to specify unguided exploration.
Status | Recruiting |
Enrollment | 80 |
Est. completion date | August 1, 2025 |
Est. primary completion date | August 1, 2025 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 45 Years |
Eligibility | Inclusion Criteria: - 20/40 far acuity (either corrected or uncorrected) - In good medical health Exclusion Criteria: - History of head injury - History of illness with Central Nervous Systems implications - On Medications that Affect blood flow response and alertness - Consumption of smoking and/or coffee 30 minutes prior to laboratory testing - Placement of a device contraindicated for magnetic resonance imaging including cardia pacemaker, aneurysm clip, cochlear implants, pregnancy, intra-uterine device, shrapnel, metal fragments in the eyes, neurostimulators - Weight > 250lbs - Claustrophobia |
Country | Name | City | State |
---|---|---|---|
United States | Temple University | Philadelphia | Pennsylvania |
Lead Sponsor | Collaborator |
---|---|
Temple University |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Mesolimbic-hippocampal Interactions | Functional Magnetic Resonance Imaging Activation characterizing mesolimbic-hippocampal interactions | During Procedure | |
Primary | Episodic Memory | Item and Associative memory for memoranda shown during the task | 24-hours after Procedure |
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