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Morbidity;Infant clinical trials

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NCT ID: NCT06444958 Completed - Morbidity;Infant Clinical Trials

Morbidity and Mortality Rates Among Children Aged 0-59 Months

Start date: January 1, 2023
Phase:
Study type: Observational

This retrospective observational study aimed to investigate the patterns of morbidity and mortality among children under 5 years of age in the population served by Kalkaal Hospital. Researchers analyzed 2023 data from the hospital's electronic medical records and administrative databases to identify the most common pediatric diagnoses and causes of illness and death in this community.

NCT ID: NCT05397678 Recruiting - Morbidity;Newborn Clinical Trials

Trial to Compare BCG-Bulgaria and BCG-Denmark

BCGSTRAIN IV
Start date: October 21, 2022
Phase: Phase 4
Study type: Interventional

The trial will be a two-year outcome assessor-blinded RCT at the maternity ward of Hospital Simão Mendes (HNSM) in urban Bissau, Guinea-Bissau to compare vaccination with Bacillus Calmette-Guérin (BCG) Danish strain (AJ Vaccines, Copenhagen 1331 strain) versus BCG-Bulgaria (BB-NCIPD, BCG-SL 222 Sofia strain) 1:1 in 15,000 infants with respect to mortality, morbidity and case-fatality rate during hospital admission. The trial will also examine the association between BCG strains and BCG skin reaction kinetics and characteristics. As a secondary aim, this large study will be used to further evaluate the role of maternal BCG immune priming for overall health, since there are indications that the maternal BCG scar status influences offspring health outcomes.

NCT ID: NCT04778735 Completed - Clinical trials for Liver Transplantation

Investigation of Mortality, Morbidity and Risk Factors After Pediatric Liver Transplantation

Start date: February 24, 2021
Phase: N/A
Study type: Interventional

The Department of Organ Transplantation in Memorial Hospitals has started Pediatric Liver Transplantation Program in 2016. As of the end of 2020, we have performed 169 pediatric liver transplantation. The aim of this study is to investigate the overall mortality, morbidity and risk factors for adverse outcomes in pediatric liver transplantation. The patients' records will be retrospectively scanned and the data will be gathered.

NCT ID: NCT04634019 Active, not recruiting - Morbidity;Infant Clinical Trials

Financially-Incentives to Improve Provider Compliance

Start date: January 1, 2018
Phase: N/A
Study type: Interventional

The main objective of this study is to assess whether making health financing streams conditional on provider performance on knowledge assessment can increase provider compliance with under-5 case management guidelines.

NCT ID: NCT04383925 Completed - Morbidity;Infant Clinical Trials

Trial to Compare Two Strains of BCG

STRAIN III
Start date: May 4, 2020
Phase: Phase 4
Study type: Interventional

The trial will be a two-year outcome assessor-blinded RCT at the maternity ward of hospital Simão Mendes (HNSM) in urban Bissau, Guinea-Bissau to compare BCG-Japan versus BCG-Russia 1:1 in 15,000 infants with respect to mortality, morbidity and case-fatality rate during hospital admission. The trial will also examine the association between BCG strains and BCG skin reaction characteristics by six weeks (data collected by telephone) and at two and six months (data collected at home-visits to a subgroup of the cohort). As a secondary aim, this large study will be used to further evaluate the role of maternal BCG immune priming for overall health, since there are indications that maternal BCG scarring enhances the non-specific effects of BCG.

NCT ID: NCT03181178 Completed - Growth Disorders Clinical Trials

Effect of a Complementary Food Supplement on Growth and Morbidity of Ghanaian Infants

TRIUMF
Start date: February 2013
Phase: N/A
Study type: Interventional

Prevention of malnutrition in infants and children requires access and intake of nutritious food starting at birth with exclusive breastfeeding for the first 6 months of life, breastfeeding in combination with complementary foods from 6-24 months of age, access to clean drinking water and sanitation, access to preventive and curative health care (including prenatal). In Ghana, the Demographic and Health Survey of 2014 reports rates of stunting, wasting and underweight in children aged 0-59 months are 28%, 14% and 9% respectively. Furthermore, height for age starts dropping from age 4-6 months with children aged 6-23 months being more likely to be stunted (40%) than those below 6 months (4%). Infant and young child feeding data show that for breast-fed children ranging from 6 months through 35 months of age, cereals are predominantly the first foods introduced in the diet (6-8 months of age). As the child grows older, consumption of fruits rich in Vitamin A, other fruits and vegetables and meat, fish, poultry and eggs are reported by the mothers. The Demographic and Health Survey (DHS) found that the proportion of breast fed children aged 6-23 months who received a recommended variety of foods the minimum number of times per day increases with child's age from 28% in children 6-8 months to 50% in children aged 18-23 months. The study objective is to examine the effect of providing a macro- and micro-nutrient fortified complementary food supplement (KokoPlusTM) on growth and nutritional status of Ghanaian infants.

NCT ID: NCT03104946 Completed - Preterm Infant Clinical Trials

To Research the Relation Between Neonatal Morbidities and Poor Outcome in Preterm Infants

Start date: September 1, 2013
Phase: N/A
Study type: Observational

From November 2014 to October 2015, a multi-centers retrospective study was conducted to collect compliance, and 8 three-level hospitals from China were included. The infants survived to a postmenstrual age of 36 week with birth weight less than 1500g and without congenital disease. The birth weight, gestational age, morbidities and poor outcomes( death, cerebral palsy, cognitive, et al) were recorded. Data were analyzed with Chi-square test to observe the relationship between morbidities and poor outcomes. And the predictive effect on the number of the top three morbidities were analyzed by Logistic regression analysis.