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Morality clinical trials

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NCT ID: NCT03883061 Recruiting - Morality Clinical Trials

Mathematical Modeling and Risk Factor Analysis for Mortality of Sepsis

Start date: January 1, 2017
Phase:
Study type: Observational [Patient Registry]

The purpose of this study was to investigate the risk factors for mortality of sepsis and to create mathematical models to predict the survival rate based on electronic health records that extracted from hospital information system. More than 1000 records should be collected and used to data analysis. Univariate and multivariable logistic regression model were applied to risk factors analysis for the outcome, and machine learn algorithms were employed to generate predictive models for the outcome.

NCT ID: NCT03859596 Completed - Morality Clinical Trials

Revisional Surgery After 925 OAGB[One Anastomosis Gastric Bypass] Operations Retrospective Cohort Study of the UK MGB/OAGB Collaborative Group.

Start date: January 1, 2010
Phase:
Study type: Observational [Patient Registry]

Background: One anastomosis Gastric Bypass/Mini Gastric Bypass (OAGB/MGB) is a new operation that provides comparable outcomes to the common bariatric procedures. Revisional surgery is still needed after a number of OAGB/MGB procedures. The aim of this study is to report the causes and management of these revisions. Methods: From 2010 -2018, 925 OAGB/MGB operations were performed at 7 bariatric units across the United Kingdom and included in this retrospective cohort study. The data was retrospectively collected and analysed. The primary end point was identification of the causes and management of revisions. Follow up ranged from 6 months to 3 years. Results: Twenty-two patients (2.3%) required revisional surgery after OAGB/MGB. Five patients (0.5%) developed severe diarrhoea managed by shortening the bilio-pancreatic limb (BPL) to 150cm. Four patients (0.4%) developed afferent loop syndrome and bile reflux was reported in another 3 (0.3%) cases; all were managed by either conversion to Roux en Y Gastric Bypass (RYGB) or a Braun anastomosis. Postoperative bleeding was controlled laparoscopically in 3 patients (0.3%). Liver decompensation was reported in 2 patients (0.2%) was treated by shortening the BPL in one patient and a reversal to normal anatomy in another. The liver failure resolved in both patients. Other indications for revision included two gastro-jejunal stenosis (0.2%), one perforated ulcer (0.1%), one patient (0.1%) with excessive weight loss and one case (0.1%) of protein malnutrition. None of the 22 patients undergoing revisional surgery after OAGB/MBG died. Lost to follow up rate was 0.2%. Conclusion: Complications requiring revisional surgery after OAGB/MGB are uncommon (2.3%) and the majority can be managed by bilio-pancreatic limb shortening, the addition of a Braun side-to-side anastomosis or conversion to RYGB. Bilio-pancreatic limb length of 200 cm or more resulted in serious complications of liver failure, protein malnutrition, excessive weight loss and diarrhoea.

NCT ID: NCT03853824 Completed - Surgery Clinical Trials

African Surgical OutcomeS-2 (ASOS-2) Trial

ASOS-2
Start date: May 6, 2019
Phase: N/A
Study type: Interventional

An international, multicentre, African cluster randomised trial. Primary objective : To determine whether increased postoperative surveillance in high-risk adult surgical patients reduces overall in-hospital mortality in surgical patients aged 18 years and over in Africa. Primary outcome measure: In-hospital mortality, censored at 30 days if the patient is still alive and in-hospital. Secondary objective: To determine whether increased postoperative surveillance in high-risk adult surgical patients reduces the overall incidence of the composite of severe in-hospital complications and mortality in adult surgical patients aged 18 years and over in Africa. Secondary outcome measure: Composite of severe in-hospital complications and mortality, censored at 30 days if the patient is still alive and in-hospital.

NCT ID: NCT03834246 Recruiting - Morality Clinical Trials

Smoke Inhalation Injury in Patients Admitted to Intensive Care

fumeintox
Start date: October 16, 2018
Phase:
Study type: Observational

Many Studies have shown that the smoke-inhalation injury is responsible for a high mortality mainly related to the systemic effects of carbon monoxide and cyanide. Respiratory lesions induced by smoke inhalation, is one of predictive factors of mortality. The aim of the study is to identify the clinical and epidemiological characteristics of smoke-inhalation injury and to identify prognostic factors among these patients .

NCT ID: NCT03817944 Completed - Morality Clinical Trials

Potato Consumption and Risk of Mortality

Start date: January 1, 1989
Phase:
Study type: Observational

Although previous studies have linked fried potato consumption with the incidence of mortality in the US population, the association between potato consumption and mortality in the Chinese population remains unknown.

NCT ID: NCT03709589 Completed - Critical Illness Clinical Trials

Comparison of Mortality Among HDU Patients With Modified Early Warning Score Cutoff of 5

Start date: December 6, 2018
Phase:
Study type: Observational

Early categorization of critically ill patients by calculating MEWS score in hospitals may give a time window for appropriate steps. If a patient is suffering from sepsis, timely intravenous fluids, early antibiotics and monitoring in a low resource country like Pakistan, may have a great impact. Therefore, the current research is planned to early identify critically ill patients by applying MEWS and reducing the mortality by providing early management and taking appropriate life saving measures. Objective: To compare frequency of mortality on 7th day of admission in HDU patients with Modified Early Warning Score at the time of admission of < 5 & ≥ 5.

NCT ID: NCT03665987 Not yet recruiting - Clinical trials for Postoperative Complications

The Effect of Preoperative Assessment Clinic on Prognosis and Economic Results of Patients With Coexisting Disease.

Start date: October 1, 2018
Phase:
Study type: Observational [Patient Registry]

To assess the effect of preoperative assessment clinic on prognosis and economic results of patients with coexisting diseases, the investigators designed a prospective cohort study. The investigators will recruit 250 patients preparing to undergo a selective epigastrium surgery with coexisting medical diseases which need an anesthetic consultation. The patients will be randomly assigned into two groups. The intervention group will be seen in the preoperative clinic before hospitalization, while the control group will get anesthetic consultation after hospitalization without clinic service. No additional interventions will be given during and after surgery. The length of stay, hospitalization expense, postoperative complication rate and mortality rate of the two groups will be compared. The investigator assume that consultation in preoperative assessment clinic will improve the prognosis and decrease the hospitalization expenses.

NCT ID: NCT03628313 Recruiting - Morality Clinical Trials

Valvular Aortic Stenosis Prognosis Study

EPRAoV
Start date: September 1, 2015
Phase:
Study type: Observational

Aortic stenosis is the most common valvulopathy in Western countries. Cardiac EchoDoppler is the reference method for assessment of aortic stenosis and provides prognostic elements. However, it is imperfect with many inconsistencies between measures. On the other hand, the prognosis of patients with low flow and low gradient aortic retraction is discussed. The main objective of this work is to study the prognosis of asymptomatic and symptomatic aortic retraction.

NCT ID: NCT03618446 Completed - Morality Clinical Trials

Predictors Of Mortality After Pelvic Fractures: A Retrospective Cohort Study From A Level-1 Trauma Center In Upper Egypt

Start date: January 1, 2010
Phase:
Study type: Observational

A retrospective cohort study was carried out for all pelvic fracture patients admitted to Assiut University Trauma Unit (AUTU), a level-1 trauma center. (AUTU) is located in Upper Egypt and provides healthcare to over 30,000 patients per year.

NCT ID: NCT03501927 Terminated - Surgery Clinical Trials

Focused Cardiac Ultrasound in Surgery

PreOPFOCUS
Start date: May 7, 2018
Phase: N/A
Study type: Interventional

Mortality and morbidity remain high after non-cardiac surgery. Known risk factors include age, high ASA grade and emergency surgery. Point-of-care focused cardiac ultrasound may elucidate pathology and potential hemodynamic compromise unknown to handling physicians. This study aims to investigate the effects of focused cardiac ultrasound in high-risk patients undergoing non-cardiac surgery with respect to clinical endpoints.