Effects of a Single Dose of Wild Blueberries on Mood and Executive Function in Healthy Emerging Adults

Mood Clinical Trial

Official title:

Effects of a Single Dose of Wild Blueberries on Mood and Executive Function in Healthy Emerging Adults: a Single-Blind, Randomized Controlled Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05717452
• Other study ID #: 2022-140-RC
• Status: Recruiting
• Phase: N/A
• Start date: February 1, 2023
• Est. completion date: April 30, 2023

Study information

• Verified date: February 2023
• Source: University of Reading
• Contact: Claire Williams, Professor
• Phone: +441183787540
• Email: claire.williams[@]reading.ac.uk
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study aims to investigate whether consuming a drink containing powdered blueberries (equivalent to 150 g of fresh fruit) can improve mood and executive function in healthy emerging adults.

Description:

The present study will examine the psychological effects of a single dose of freeze-dried wild blueberries using a randomized, single-blind, placebo-controlled design. A total of 80 participants will be randomly allocated to consume either a drink prepared with 22 g blueberry powder or a drink prepared with 22 g placebo powder matched for macronutrients, flavour and colour.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 80
• Est. completion date: April 30, 2023
• Est. primary completion date: April 30, 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 25 Years

Eligibility

Inclusion Criteria:

• 18 to 25 years of age

Exclusion Criteria:

• Any medically significant condition or mental health disorder (e.g. diabetes, endocrine or gastrointestinal disorders)
• Taking medication (excluding hormonal contraception or medication for asthma/seasonal allergies)
• Allergy to blueberries or any other Vaccinium species

Related Conditions & MeSH terms

• Affect
• Executive Function
• Mood

Intervention

Dietary Supplement:
• Blueberry drink
22 g freeze-dried wild blueberry (Vaccinium angustifolium) powder mixed with 250 ml water.
• Placebo drink
22 g placebo powder matched for macronutrients, color, and flavor mixed with 250 ml water.

Locations

Country	Name	City	State
United Kingdom	School of Psychology and Clinical Languages, University of Reading	Reading	Berkshire

Sponsors (2)

Lead Sponsor	Collaborator
University of Reading	Wild Blueberry Association of North America (WBANA)

Country where clinical trial is conducted

United Kingdom, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Positive affect as measured by PANAS-X	Positive affect will be calculated by adding the values of the 21 positive items of the Positive and Negative Affect Schedule-X and the additional item "motivated". Thus, the scale will range from 0 to 88 points with higher scores indicating better mood.	1.5 hours post-ingestion
Secondary	Negative affect as measured by PANAS-X	Negative affect will be calculated by adding the values of the 25 negative items of the Positive and Negative Affect Schedule-X. Thus, the scale will range from 0 to 100 points with higher scores indicating worse mood.	1.5 hours post-ingestion
Secondary	Executive function (accuracy)	A task-switching test will be used to assess cognitive flexibility when switching between two predictable tasks requiring simple numerical decisions. The main outcome of interest is the average accuracy (0 to 100%).	1.5 hours post-ingestion
Secondary	Reaction time	The average reaction time on correct trials of the task-switching test (in milliseconds).	1.5 hours post-ingestion