Clinical Trials Logo
  1. Home
  2. Mood
  3. NCT02051530

Mood, Serotonin and Social Interaction

Mood Clinical Trial

Official title:
Mood, Serotonin and Social Interaction

Clinical Trial Summary

Rationale: Major depressive disorder (MDD) is a psychiatric disorder whose onset, severity, and duration are influenced by interpersonal factors. The serotonin system is known to influence MDD risk. Recent research has suggested that serotonin may also play a role in regulating social behaviour. Therefore, it would be interesting to study the role of serotonin in responses to social stimuli in individuals at risk for MDD.

Objective: This project aims to study how changes in serotonin alter interpersonal functioning in adults with or without a first degree family member diagnosed with MDD. The primary goal is to investigate the effect of experimentally lowered brain serotonin levels on empathic accuracy. Secondary goals are to determine how this manipulation influences verbal and non-verbal communication, cardiovascular function in a social context, and mood. An exploratory goal is to investigate how these outcomes are related to genes thought to be involved in MDD.

Clinical Trial Description

see summary ;

Study Design

Allocation: Randomized, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Basic Science

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02051530
Study type Interventional
Source University of Groningen
Contact
Status Completed
Phase Phase 0
Start date April 2012
Completion date March 2014
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05234476 - Behavioral Activation Plus Savoring for University Students N/A
Active, not recruiting NCT05516264 - Behavioural and Physiological Responses to Dog Visits in Nursing Homes N/A
Completed NCT05555186 - The Effects of Bright Light Therapy on Adolescent's Sleep Quality and Well-being N/A
Completed NCT04706806 - Effect of Daily Vinegar Ingestion for Four Weeks on Mood State in Healthy College Students N/A
Completed NCT04013451 - The Kiss of Kindness Study II N/A
Completed NCT03689348 - Acute and Chronic Effects of Avena Sativa on Cognition and Stress N/A
Completed NCT04440553 - A Mobile App to Increase Physical Activity in Students N/A
Completed NCT04505800 - Tryptophan Supplementation to Improve Night Shift Workers' Health N/A
Active, not recruiting NCT06082778 - ZOE's Ferment Experiment N/A
Completed NCT05100589 - Effect of PeakATP on Mood, Reaction Time and Cognition N/A
Completed NCT05559372 - Energy Drink Effects on Performance, Mood, and Cardiovascular Outcomes N/A
Active, not recruiting NCT04641689 - Stand Up Kansas: An Intervention to Reduce Sedentary Behavior in the Home Work Environment N/A
Active, not recruiting NCT01725425 - The Effect of Portion Sizes on Mood N/A
Completed NCT01794351 - Cognitive Effects of 500mg Trans-resveratrol N/A
Completed NCT05550610 - Evaluation of Mindfulness and Yoga in Basic Combat Training N/A
Recruiting NCT05939453 - Impact of Bright Light Therapy on Prader-Willi Syndrome N/A
Recruiting NCT05058872 - Contraceptive Hormone and Reward Measurement (CHARM Study) Phase 4
Not yet recruiting NCT04551274 - Music Therapy in Frontline Healthcare Workers N/A
Completed NCT03105973 - Technology Enabled Mental Health Intervention for Individuals in the Criminal Justice System N/A
Completed NCT04075448 - The Acute Effect of a Walnut Intervention on Cognitive Performance, Brain Activation, and Serum Markers of Inflammation in Young Adults N/A