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Mood Management clinical trials

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

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NCT ID: NCT00075972 Completed - Smoking Cessation Clinical Trials

Mood and Smoking: A Comparison of Smoking Cessation Treatments

Start date: March 2003
Phase: N/A
Study type: Interventional

Objectives: The long term objectives of this research program are: 1. To advance the mission of the VHA Boston Healthcare System to deliver comprehensive quality healthcare that meets the needs of patients (in this case, who have been unresponsive to standard smoking cessation treatment) through research and clinical care. 2. To expand upon our knowledge of the feasibility and effectiveness of commonly-used treatments for nicotine dependence. 3. To further explore variables related to mood and coping that may contribute to or prevent successful reduction and cessation of smoking behavior among veterans. The short-term objectives of this project are: 1. To evaluate the feasibility and effectiveness of two adjunctive treatments (a mood-focused exposure-based treatment, Mood Tolerance, with Nicotine Replacement Therapy [MTNRT] and mood-focused affect-management treatment, Mood Management, with Nicotine Replacement Therapy [MMNRT]) aimed at reduction and cessation of smoking behavior among veterans who were previously non-responders to smoking cessation treatment in the VA. 2. To inform equivocal findings in the literature regarding the role of mood as trigger for smoking behavior. 3. To explore selected mood, coping, and individual difference variable that may be predictive of successful abstinence from cigarettes among veterans.