Brain Emotion Circuitry-Targeted Self-Monitoring and Regulation Therapy (BE-SMART) — BE-SMART  

Mood Disorders Clinical Trial

Official title: Brain Emotion Circuitry-Targeted Self-Monitoring and Regulation Therapy (BE-SMART)

Status Completed

Clinical Trial Summary

New treatments to help to reduce the emotional dysregulation of mood disorders are critically needed. This is a study of an emotional dysregulation psychotherapy treatment in which participants will learn skills to help to down-regulate maladaptive emotional responses and learn beneficial, healthy habits. Investigators will perform symptom and behavioral assessments and scanning prior to the treatment and will then repeat scanning, symptom and behavioral assessments at the midpoint, and after the psychotherapy is completed. This collected information will assess whether the treatment can improve functioning of emotion regulation brain circuitry.

Clinical Trial Description

Aim: To use functional magnetic resonance imaging (fMRI), before, at mid point, and after an emotional regulation intervention, to assess intervention-associated changes in brain circuitry responses to emotional stimuli.

Hypothesis : The emotional regulation psychotherapy treatment will be associated with changes in emotional regulation circuitry.

At the time of registration, the primary outcome "Changes in Functioning of Emotional Brain Circuitry" was the only outcome registered. This outcome is comprised of multiple measurements and was split up individually at the time of results entry and the original primary outcome measure was deleted. ;

Related Conditions & MeSH terms

• Mood Disorders

• NCT number: NCT03183388
• Study type: Interventional
• Source: Yale University
• Status: Completed
• Phase: N/A
• Start date: October 17, 2017
• Completion date: June 30, 2022