Mood Disorders Clinical Trial
Official title:
Double-Blind, Placebo-Controlled Study of Depakote (Divalproex Sodium) in Children With Temper Outbursts and Severe Mood Swings
The purpose of this study is to determine the effectiveness of divalproex sodium (Depakote) versus placebo in treating children with temper outbursts and severe mood disorders.
Depakote has been used to treat seizures in children for more than 20 years. The purpose of
this study is to determine the effectiveness of divalproex sodium (Depakote) in treating
children with temper outbursts and severe mood disorders.
This study will last 12 weeks. Participants will be randomly assigned to receive either 250
mg Depakote or placebo. The dose of medication will increase at the end of Week 1 to 500 mg
of either depakote or placebo; participants will remain on this dose through Week 5. At Week
6, participants will cross-over and receive the other treatment (either depakote or
placebo), which they will take through Week 12. Study visits will occur weekly and will
include a physical exam, blood and urine tests, and self-reports of adverse events. In
addition, caregivers will complete reports about mood swings throughout the study.
;
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Double-Blind, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT05321602 -
Study to Evaluate the PK Profiles of LY03010 in Patients With Schizophrenia or Schizoaffective Disorder
|
Phase 1 | |
| Recruiting |
NCT05345392 -
Brain, Emotions, and Mind-Wandering
|
N/A | |
| Completed |
NCT05078450 -
Mood Lifters Online for Graduate Students and Young Professionals
|
N/A | |
| Not yet recruiting |
NCT04551027 -
Assessing the Effect of Compensatory Cognitive Intervention Among People With Severe Mental Illness
|
N/A | |
| Recruiting |
NCT03088657 -
Design and Methods of the Mood Disorder Cohort Research Consortium (MDCRC) Study
|
||
| Active, not recruiting |
NCT02542475 -
Low Field Magnetic Stimulation: Open Label Study.
|
Phase 1/Phase 2 | |
| Completed |
NCT00916552 -
Effects of Erythropoietin on Depressive Symptoms and Neurocognitive Deficits in Depression and Bipolar Disorder
|
Phase 2 | |
| Completed |
NCT00202514 -
Placebo Controlled Trial of Depakote ER in Alcohol Dependent Patients With Mood and/or Anxiety Symptoms
|
Phase 2/Phase 3 | |
| Completed |
NCT00006517 -
Clinical Trials of Three Non-Drug Treatments for Winter Depression (SAD)
|
N/A | |
| Terminated |
NCT03898843 -
Assisted Animal Therapy: ReAnimal
|
N/A | |
| Active, not recruiting |
NCT04358900 -
Unobtrusive Monitoring of Affective Symptoms and Cognition Using Keyboard Dynamics (UnMASCK)
|
||
| Recruiting |
NCT06360562 -
Reconnecting to Ourselves and Others in Virtual Meetings (ROOM)
|
N/A | |
| Completed |
NCT05745103 -
Optimizing Behavioral Healthcare Delivery Through Technology
|
N/A | |
| Suspended |
NCT03715400 -
Mobile Virtual Positive Experiences for Anhedonia
|
N/A | |
| Enrolling by invitation |
NCT03736538 -
Nitrous Oxide- Suicidal Ideation
|
Phase 1 | |
| Completed |
NCT04601545 -
The Virtual Reality Therapy as a Pulmonary Rehabilitation Supporting Method
|
N/A | |
| Completed |
NCT02566980 -
Biological Triggers of Depression in Pregnancy
|
||
| Completed |
NCT03743844 -
Psychosocial Intervention for Women With Mood Disorders Seeking Treatment for Obesity
|
N/A | |
| Completed |
NCT05211063 -
Effects of CROCUVIS+® on Computer Vision Syndrome, Sleep and Mood Disorders
|
N/A | |
| Completed |
NCT02766101 -
Manville Moves: an Exercise Intervention for Behavioral Regulation Among Children With Behavioral Health Challenges
|
N/A |