Clinical Trials Logo

Clinical Trial Summary

This is a randomized, placebo-controlled, double-blind, 3 parallel-arm study in pregnant women aged 21 years old and above. The study aims to assess changes in perinatal mood and stress when administering a probiotic starting from either the 3rd trimester (i.e 28-32 weeks of gestational age) or immediately after birth, until 12 weeks post-partum.


Clinical Trial Description

To date, limited evidence is available for nutritional interventions in the role of modulation of perinatal mood and stress, even less so for probiotics. The probiotic strain Bifidobacterium longum (BL) NCC3001 has previously been shown to normalize anxiety-like behavior in preclinical models and to reduce feelings of low mood and emotional reaction to fearful stimulus in human adults with irritable bowel syndrome (IBS). The strain is also considered safe and has previously been administered to pregnant and lactating women as well as infants. Therefore, the study aims to evaluate the effect of probiotic (BL) NCC3001 on mood and stress levels during the perinatal period. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04685252
Study type Interventional
Source Société des Produits Nestlé (SPN)
Contact
Status Completed
Phase N/A
Start date November 6, 2020
Completion date May 20, 2022

See also
  Status Clinical Trial Phase
Completed NCT05684614 - Interoception and Emotion Regulation
Completed NCT03695003 - Cognitive Effects of Sage in Healthy Humans N/A
Completed NCT04081662 - Examining the Efficacy of Acceptance and Commitment Therapy (ACT) Microinterventions for Distressed First-Generation College Students Phase 1
Not yet recruiting NCT05948410 - How Does the Mood of the Patients Change Before and After the Invasive Urodynamic Study?
Recruiting NCT06441695 - Acute Effects of PLT Health Solutions zümXR Extended-Release Caffeine N/A
Completed NCT05051501 - The Effects of Microbiological Spectrum Changes to Improve Cognitive Health in Aging Population Phase 2
Withdrawn NCT05252598 - Mood and Cognitive Effects of Psilocybin in Healthy Participants Early Phase 1
Completed NCT05160220 - Naturalistic Study of Microdosing With Psilocybin N/A
Completed NCT05795322 - Acute Effect of Sound Healing on Pain, Fatigue and Mood
Active, not recruiting NCT06309914 - The Effects of Mirtoselect®, Virtiva®, and Enovita® on Cognitive Performance and Mood States N/A
Recruiting NCT05212389 - The Pill Project - Oral Contraceptive and Serotonergic Brain Signaling N/A
Completed NCT05504668 - The Cognitive Effects of 'Brainwaves' Supplementation in Cognitively Intact Older Adults N/A
Recruiting NCT05363228 - The Effect of Tai Chi and Therapy by Dance and Movement on Blood Irisin Levels in Older Adults Over 65 Years of Age. N/A
Recruiting NCT05447689 - Mind-Body Skills Group for Graduate Students N/A
Completed NCT03499379 - Stress Hormones and IUDs