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Molar Incisor Hypomineralization clinical trials

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NCT ID: NCT03760497 Recruiting - Clinical trials for Molar Incisor Hypomineralization

Three Restorative Protocols in MIH: a Randomized Controlled Clinical Study

Start date: December 2021
Phase: N/A
Study type: Interventional

Molar-Incisive Hipomineralization (MIH) is defined as a qualitative change in tooth enamel of systemic origin, which affects one or more permanent first molars, and may or may not involve permanent incisors. MIH has several clinical repercussions, such as presence of hypersensitivity, difficulty in local anesthesia, reduction of restorations longevity, among others, making it difficult to perform dental treatment. Therefore, the present study will evaluate, through a randomized controlled clinical study, three restorative protocols for the treatment of severe MIH (with post eruptive enamel fracture and dentin exposure). The following groups will be evaluated: direct restoration with composite resin; restoration with composite resin with diode laser application and temporary restoration with glass ionomer cement followed by restoration with composite resin). The restorations will be evaluated after 1 week, 1, 6, 12, 18 and 24 months. The main outcome will be evaluation of restoration longevity, presence of caries lesion and wear of the restoration surface. Other outcomes such as patient satisfaction with treatment, patient discomfort, anxiety, assessment of dentin sensitivity and impact on participants' quality of life, as well as the duration and cost of treatment, as well as their cost-effectiveness ratio will also be evaluated . Multilevel statistical analyzes will be performed to verify the effectiveness of diode laser treatment compared to sealing, in addition to possible factors associated with this efficacy.

NCT ID: NCT03735069 Completed - Clinical trials for Molar Incisor Hypomineralization

Vital Pulp Therapy in Carious Teeth With Hypomineralization

Start date: September 12, 2017
Phase: N/A
Study type: Interventional

Vital pulp therapy (VPT) is a general term for multiple procedures (indirect pulp cap, direct pulp cap and pulpotomy) all directed toward preserving pulp vitality and enable complete root development in immature teeth. The aim of this study is to evaluate the clinical, radiographic and histologic (if any teeth later are doomed for extraction for orthodontic or other reasons) success rate of VPT on treating cariously exposed permanent teeth with developmental defects of enamel. This will be a a prospective case series study including children between 6-16 years old having tooth with enamel hypomineralization defect with deep caries, restorable teeth , and no signs of infection. The teeth will be followed up both clinically and radiographically for 1 year after treatment. It is expected that the teeth will maintain vitality with resolution of symptoms (if present) and completion of root development in immature teeth after vital pulp therapy.

NCT ID: NCT03583671 Not yet recruiting - Clinical trials for Molar Incisor Hypomineralization

Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children From 8 to 12 Years Old in Dakahlia

MIH
Start date: November 2018
Phase:
Study type: Observational

The aim of this study is to assess the prevalence of MIH among a group of Egyptian children aged from 8-12 years old in Dakahlia governorate schools.

NCT ID: NCT03498209 Not yet recruiting - Clinical trials for Molar Incisor Hypomineralization

Prevalence of Molar Incisor Hypominerlization (MIH) Among a Group of Egyptian Children

MIH
Start date: May 20, 2018
Phase:
Study type: Observational

To determine the Prevalence of MIH in a group of Egyptian children attending the Pediatric Dentistry and Dental Public Health Department, Faculty of Dentistry, Cairo University.

NCT ID: NCT03233464 Enrolling by invitation - Clinical trials for Molar Incisor Hypomineralization

Prevalence of Molar Incisor Hypomineralization Among a Group of Egyptian Children in Giza Governorate

MIH
Start date: May 2018
Phase: N/A
Study type: Observational [Patient Registry]

- One single operator will assess the prevalence of molar incisor hypomineralization and its Severity among a group of Egyptian children .

NCT ID: NCT02794116 Completed - Clinical trials for Molar Incisor Hypomineralization

Sealants in Molars Affected by Molar-Incisor Hypomineralization

Start date: January 2012
Phase: N/A
Study type: Interventional

Aim: To evaluate the clinical survival of fluoride sealants applied in first permanent molars affected by Molar-Incisor Hypomineralization (MIH). Material and Methods: For this case control study, it was selected 41 first permanent molars of the 21 children aged 6-8 years. MIH was classified by one calibrated examiner (kappa 0.80) according severity of the MIH lesion (EAPD, 2003). Inclusion criteria were FPM with MIH or sound (without MIH), fully erupted, and with sealant treatment indication. The FPMs were assigned into two groups: G1 - Control group and G2 - MIH group. Both group teeth were treated with sealant application (Fluroshield, NY, USA). Clinical follow-up was performed at baseline, 1, 6, 12 and 18 months for anatomic form, marginal adaptation, retention and presence of caries, according to the United States Public Health Service USPHS-Modified by a blinded examiner (kappa 0.80). The Acturial Method was used to evaluate the survival of sealants. Statistical analysis compared the ratings of each criterion between materials using the Fisher's exact test at a level of significance of 5% (p<0.05).

NCT ID: NCT02717286 Completed - Clinical trials for Molar Incisor Hypomineralization

Restorative Treatment in First Molars Affected by Molar-Incisor Hypomineralization

Start date: January 2013
Phase: N/A
Study type: Interventional

The restorative management of molars with Molar-Incisor Hypomineralization (MIH) represents a challenge in the clinical practice with high failure rate. Thus, this clinical trial aimed to evaluate the clinical survival of direct composite resin restorations in first permanent molars (FPMs) that are affected by MIH, comparing two adhesive systems.