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Expressions of TRPV1 in Airway of Asthmatics — TRPV1  

Pulmonary Atelectasis Clinical Trial

Official title:
Expressions of TRPV1 in Airway of Asthmatics

Clinical Trial Summary

The purpose of this study is to measure the density of a temperature-sensitive protein, named TRPV1, in the airway mucosa tissue of both non-asthmatic and moderate to severe persistent asthmatic patients. This study may generate information for developing new therapeutic strategy.

Clinical Trial Description

The research procedure will be conducted at University of Kentucky A.B. Chandler Hospital dedicated bronchoscopy suite located on third floor of Pavilion H module room #2, and will be performed only once as part of a standard of care bronchoscopy procedure scheduled by the participants pulmonary physician. This entire study (biopsy) will add 10 minutes or less. Following the biopsy, and after being discharged from the hospital, the participant's study participation will end. Bronchial Biopsy: The investigator will collect five lung (bronchial) specimens (1-2 cubic millimeters each) from three zones of the participant's airway which will be individually coded, and stored for the computer image analysis of TRPV1 in the investigator's laboratory. Following analysis the samples will be destroyed. The results of the analysis cannot be used for determining a clinical diagnosis. Therefore, the investigator will not provide any findings to either the participant or their physician. Participants will not get any personal benefit from taking part in this study. Their willingness to take part in this research study, may, in the future help doctors better understand and/or treat patients with asthma. There will be no cost to the participant for having the bronchial biopsy performed. Participants will not receive any rewards or payment for taking part in the study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02952066
Study type Interventional
Source University of Kentucky
Contact
Status Withdrawn
Phase N/A
Start date September 20, 2017
Completion date November 20, 2018
View Details
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