Mitral Valve Prolapse Clinical Trial
Official title:
Exercise Capacity Evaluation in Patients With Non-rheumatic Mitral Valve Prolapse (MVP)
Mitral valve prolapse (MVP) is a relatively common cardial problem in which one or more of
the leaflets of the mitral valve prolapse during systole into the left atrium.
The disease is very heterogeneous and can vary from a benign disease with almost no impact
on the patient's life to a severe cardiac problem with many complications and high mortality
rate.
The purpose of the study is to see if the investigators can find a relation between the
severity of the MVP to the exercise capacity of the patient. The investigators also want to
see if they can find a difference between the exercise capacity of mild MVP patients and
healthy people.
To evaluate the exercise capacity of the subjects the investigators use Cardiopulmonary
Exercise Testing (CPET). CPET is probably the best known way to get a full picture of the
subject's functions during exercise. By combining gas exchange monitoring and ECG during a
controlled exercise in which the subject reaches maximal effort, the test gives information
about the cardiac, the pulmonary and the metabolic functions of the subject. This
information can help identify if there is a problem to perform exercise properly and more
specifically if the limitation is due to a cardiac, pulmonary or metabolic problem.
Mitral valve prolapse (MVP) is a relatively common cardial problem in which one or more of
the leaflets of the mitral valve prolapse during systole into the left atrium.
The disease is very heterogeneous and can vary from a benign disease with almost no impact
on the patient's life to a severe cardiac problem with many complications and high mortality
rate .
The purpose of the study is to see if the investigators can find a relation between the
severity of the MVP to the exercise capacity of the patient. The investigators also want to
see if they can find a difference between the exercise capacity of mild MVP patients and
healthy people.
To evaluate the exercise capacity of the subjects the investigators use Cardiopulmonary
Exercise Testing (CPET). CPET is probably the best known way to get a full picture of the
subject's functions during exercise. By combining gas exchange monitoring and ECG during a
controlled exercise in which the subject reaches maximal effort, the test gives information
about the cardiac, the pulmonary and the metabolic functions of the subject. This
information can help identify if there is a problem to perform exercise properly and more
specifically if the limitation is due to a cardiac, pulmonary or metabolic problem.
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Observational Model: Case Control, Time Perspective: Prospective
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