TEER for Severe DMR of Low to Intermediate Surgery Risk

Status Recruiting

Clinical Trial Summary

To investigate the efficacy and safety of transcatheter mitral valve edge-to-edge repair (TEER) for severe degenerative mitral regurgitation (DMR) patients of low to intermediate surgery risk.

Clinical Trial Description

This is a proposed multicentre, prospective cohort study to enrol and follow up severe DMR patients of low to intermediate surgery risk who underwent TEER, and surgical historical controls. The primary efficacy endpoints are all-cause death and cumulative composite event rate of worsening heart failure at 24 months postoperatively, and the primary safety endpoints are death, secondary surgery, and various complications at 30 days postoperatively. The study aims to investigate the efficacy and safety of TEER in surgical low-intermediate-risk patients with severe DMR, and to inform the subsequent clinical application. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT06162780
Study type	Observational [Patient Registry]
Source	Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Contact	Yangxin Chen, PhD
Phone	8681332360
Email	chenyx39@mail.sysu.edu.cn
Status	Recruiting
Phase
Start date	January 1, 2024
Completion date	December 2026

View Details

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