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Physiological Changes of the Mitral Annulus After Annuloplasty in Barlow Disease

Mitral Insufficiency Clinical Trial

Official title:
Physiological Changes of the Mitral Annulus After Annuloplasty in Barlow Disease: an MRI-focused Study

Clinical Trial Summary

Barlow disease (BD) is a common cause of mitral insufficiency. In 2012 the University Hospital of Basel started to perform a simplified mitral valve repair technique in BD just by implanting an annuloplasty-ring. It is hypothesized that the major mechanism of the valvular insufficiency in Barlow disease is a deformation of the left ventricle and the posterior mitral annulus, causing its aberrant displacement during the systole towards posterior and basal and thus impairing the coaptation of the leaflets. This prospective individual MRI study is to investigate the ventricle and the mitral annulus pre- and postoperatively for detailed analysis.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04418960
Study type Observational
Source University Hospital, Basel, Switzerland
Contact Martin Grapow, Prof. Dr. med.
Phone +41 44 3873711
Email grapow@herzzentrum.ch
Status Recruiting
Phase
Start date September 21, 2018
Completion date April 2022
View Details
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