Study the Effect of Neurectomy of Nasopalatine Nerve on Sensation of Anterior Palate

Missing Teeth Clinical Trial

Official title:

Effect of Neurectomy of Nasopalatine Nerve on Sensation of Anterior Palate in Patient Undergoing Rehabilitation of Atrophic Anterior Maxillary Ridge With Dental Implant

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04153851
• Other study ID #: OMFS 6-3-1
• Status: Recruiting
• Phase: N/A
• Start date: December 1, 2019
• Est. completion date: December 31, 2021

Study information

• Verified date: November 2019
• Source: Cairo University
• Contact: Abdelmoez Elsharkawy, lecturer
• Phone: 01223194207
• Email: moezshark[@]gmail.com
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Study the effect of neurectomy of nasopalatine nerve on the sensation of anterior palate in patients undergoing rehabilitation of anterior maxillary ridge with dental implant

Description:

Replacement of missing teeth in the anterior maxilla could be challenging if enlargement of the nasopalatine canal which is located in the midline of the palate posterior to the maxillary central incisors or ridge atrophy occur after tooth extraction. This could place the neurovascular content of the nasopaltine canal in the path of the dental implant which may lead to complications such as nasopalatine canal cyst, sensory dysfunction or implant failure. Technique to overcome this problem have evolved including neurectomy of the nasopalatine canal content and obliteration of canal with bone graft.

Loss of sensation in anterior palate following this procedure could be an annoying complication for patients. In recent studies regaining of sensation following such procedure have been reported, Confirmation of such results is essential to rule out the side effect of loss of sensation in the anterior palatal region

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 1
• Est. completion date: December 31, 2021
• Est. primary completion date: December 31, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• • Adult patients requiring dental implants placement in the anterior region of maxilla and has insufficient horizontal bone .

• Patients should be free from any systemic conditions that may affect soft tissue healing.

Exclusion Criteria:

• • Patients with systematic disease that may complicate healing.

• Uncontrolled diabetic patient.

• Patients with advanced osteoporosis.

• Patients under bisphosphonates treatment.

• Patients with neurological disorders (neuralgias, Parkinson's disease).

• Patients with horizontal ridge atrophy (if the horizontal dimension of the residual ridge <3mm as determined with ridge callipers).

• Heavy smoker patients.

Related Conditions & MeSH terms

• Anodontia
• Missing Teeth
• Tooth Loss

Intervention

Procedure:
• neurectomy of nasopalatine nerve
Severing of nerurovascular bundle and pushing the nasopalatine canal content nasally and insertion of bone graft in the canal. Dental implant will be inserted in the central incisor location

Locations

Country	Name	City	State
Egypt	Cairo university	Cairo

Sponsors (1)

Lead Sponsor	Collaborator
Cairo University

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	two point discrimination test	This test will be performed using a calliper, the two points of the calliper are opened progressively in 1mm increments and care should be taken that the two points are touching the mucosa in the same time until the patient can discriminate two points of contact at which the distance between the two points is recorded	six months