Behavioral and Pharmacological Reconsolidation Interference in Misophonia — Miso Prop

Misophonia Clinical Trial

Official title:
Misophonia-Related Memory Modification Using Reconsolidation Mechanisms: Pharmacological and Behavioral Manipulation

Status Enrolling by invitation

Clinical Trial Summary

One of the core processes presumably underlying misophonia - a condition characterized by decreased tolerance for specific sounds - is associative learning. Using behavioral, computational, and neural analyses of emotional learning and memory processes to understand the unknown behavioral and neural mechanisms underlying misophonia's associative learning and memory, the study team will evaluate whether interference with the reconsolidation of a reactivated misophonia memory with propranolol can alleviate aversive reaction to misophonia-related cues.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Misophonia

Clinical Trial Details

NCT number	NCT05928689
Study type	Interventional
Source	Icahn School of Medicine at Mount Sinai
Contact
Status	Enrolling by invitation
Phase	Early Phase 1
Start date	June 2, 2023
Completion date	October 2024

View Details

See also
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Recruiting	`NCT06333925` - Using Neurostimulation to Accelerate Change in Misophonia: a Pilot Study	N/A
Completed	`NCT05993286` - Treatment of Misophonia: Comparison of Exposure and Sound Therapy	N/A
Completed	`NCT04612374` - Exploring the Acceptability and Efficacy of a Transdiagnostic Treatment for Misophonia	N/A
Recruiting	`NCT04365543` - Treatment for Youth (Ages 8 to 16 Years Old) With Misophonia (U-HEAR)	N/A