Mitral Valve Prolapse Clinical Trial
Official title:
Endo-aortic Versus Trans-thoracic Clamping in Right Mini-thoracotomy Mitral Valve Repair: Outcome on Myocardial Pro-tection
Perfusion strategies and aortic clamping techniques for right mini-thoracotomy mitral valve
(MV) surgery have evolved over time and remarkable short- and long-term results have been
re-ported. However, some concerns have emerged about the adequacy of myocardial protection
dur-ing the minimally invasive approach and about the role of aortic clamping strategies in
this contest.
Aim of this study was to compare the efficacy, in terms of myocardial protection, of the
en-do-aortic clamp (EAC) versus the trans-thoracic aortic clamp (TTC) in patients undergoing
right mini-thoracotomy MV repair.
A single center, prospective observational study was performed between June 2014 to June 2018
on patients undergoing right mini-thoracotomy MV repair with retrograde arterial perfusion
and EAC or TTC. The selection of one setting in respect to the other was patient orientated.
Myocardial protection was assessed through creatinine kinase-myocardial band (CK-MB) and
cardiac Troponin T (cTn-T) blood levels immediately after the surgical procedure and at 6,
12, and 24 hours and compared between the two groups.
n/a
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