Mitral Valve Prolapse Clinical Trial
Official title:
Endo-aortic Versus Trans-thoracic Clamping in Right Mini-thoracotomy Mitral Valve Repair: Outcome on Myocardial Pro-tection
Perfusion strategies and aortic clamping techniques for right mini-thoracotomy mitral valve
(MV) surgery have evolved over time and remarkable short- and long-term results have been
re-ported. However, some concerns have emerged about the adequacy of myocardial protection
dur-ing the minimally invasive approach and about the role of aortic clamping strategies in
this contest.
Aim of this study was to compare the efficacy, in terms of myocardial protection, of the
en-do-aortic clamp (EAC) versus the trans-thoracic aortic clamp (TTC) in patients undergoing
right mini-thoracotomy MV repair.
A single center, prospective observational study was performed between June 2014 to June 2018
on patients undergoing right mini-thoracotomy MV repair with retrograde arterial perfusion
and EAC or TTC. The selection of one setting in respect to the other was patient orientated.
Myocardial protection was assessed through creatinine kinase-myocardial band (CK-MB) and
cardiac Troponin T (cTn-T) blood levels immediately after the surgical procedure and at 6,
12, and 24 hours and compared between the two groups.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT02499419 -
Exercise Capacity Evaluation in Patients With Non-rheumatic Mitral Valve Prolapse (MVP)
|
N/A | |
| Completed |
NCT02512341 -
Automatic Differentiation of Innocent and Pathologic Murmurs in Pediatrics
|
||
| Completed |
NCT02105480 -
Automated Algorithm Based Analysis of Phonocardiograms of Newborns
|
||
| Enrolling by invitation |
NCT04067635 -
Primary Mitral Regurgitation Repair
|
||
| Recruiting |
NCT06378996 -
Arrhythmic Mitral Valve Prolapse Detection Using Long-term Ambulatory Rhythm Monitoring
|
N/A | |
| Terminated |
NCT03285724 -
Safety and Performance Study of the Harpoon Mitral Valve Repair System
|
N/A | |
| Recruiting |
NCT03506217 -
Using Pulse Counter Vigileo-Flotrac System in Transapical Off-pump Minimally Invasive Mitral Valve Repair
|
||
| Completed |
NCT00665301 -
Cardiac Output Pulmonary Arterial Catheter Compared to FloWave™ 1000
|
N/A | |
| Not yet recruiting |
NCT04299334 -
Neochordae Technique in Mitral Valve Repair
|
Phase 1 | |
| Completed |
NCT03470155 -
Operative Mitral Valve Reconstruction in Functional mv Insufficiency With Reduced Systolic Ventricle Function
|
||
| Recruiting |
NCT06341166 -
Multiparametric SCores for Prediction of Myocardial fIbrosis in Patients With MITral vAlve pRolapse
|
||
| Not yet recruiting |
NCT03609931 -
Patient Specific Mitral Valve Modeling for Surgical Planning and Training
|
||
| Recruiting |
NCT05631730 -
Effect and Safety of Flecainide and Metoprolol Versus Metoprolol Alone to Suppress Ventricular Arrhythmias in Arrhythmic Mitral Valve Prolapse
|
Phase 3 | |
| Recruiting |
NCT02552771 -
The Canadian Mitral Research Alliance (CAMRA) Trial CardioLink-2
|
N/A | |
| Recruiting |
NCT01719211 -
Genetic Basis of Mitral Valve Prolapse
|
||
| Recruiting |
NCT04190602 -
Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System
|
||
| Recruiting |
NCT03113552 -
Prognostic Impact of the Location of Mitral Valve Prolapse on the Long-term Results of Mitral Plasty
|
||
| Recruiting |
NCT06255457 -
Ventricular Arrhythmias in Patients Undergoing Mitral Valve Surgery
|
||
| Completed |
NCT02771275 -
Safety and Early Feasibility Study of the Harpoon Medical Device (EFS)
|
N/A | |
| Recruiting |
NCT05562804 -
Mitral Valve Prolapse, Arrhythmias and Mitral Valve Surgery
|