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Minimally Conscious State clinical trials

View clinical trials related to Minimally Conscious State.

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NCT ID: NCT03732092 Completed - Clinical trials for Minimally Conscious State

The Effects of Olfactory Stimulation on Diagnosis and Prognosis of DOC Patients

Start date: March 15, 2018
Phase:
Study type: Observational

Analyze the behavioral response of patients with disorders of consciousness through olfactory stimulation, compare the response of olfactory stimulation in patients with different consciousness, and analyze the impact of olfactory stimulation on diagnosis; After the first, third, and sixth months of initial enrollment, the recovery of prognosis was tracked by the Coma Recovery Scale-Revision (CRS-R).

NCT ID: NCT03508336 Completed - Clinical trials for Minimally Conscious State

The Initiation of Swallowing Can Indicate the Prognosis of DOC

Start date: June 3, 2016
Phase:
Study type: Observational

This study is aimed to detect the initiation of swallowing act in DOC patients, to find if it is a good item as a stimulus and to detect the relationship between the initiation of swallowing act and the prognosis of DOC patients.

NCT ID: NCT03494218 Completed - Clinical trials for Minimally Conscious State

Reliability and Validity of the NCS (NCS-R)-Chinese Version

Start date: October 28, 2017
Phase: N/A
Study type: Interventional

The aim of this study was to translate the NCS from English into Chinese and determine the validity of this Chinese version.

NCT ID: NCT03492294 Completed - Clinical trials for Minimally Conscious State

The Role of Music Stimulation in Disorders of Consciousness State: an fMRI Study

Start date: December 2008
Phase:
Study type: Observational

The aim of the present study was to evaluated the neural effect of music on the cerebral activation in unresponsive wakefulness syndrome (UWS) and minimally conscious state (MCS) by using functional magnetic resonance imaging (fMRI).

NCT ID: NCT03126929 Completed - Clinical trials for Minimally Conscious State

Further Psychometric Data for the Reliability and the Diagnostic Validity of CRS-R

Start date: March 2012
Phase: N/A
Study type: Observational

This study aims to provide, in a large sample, further psychometric data as regards the internal consistency, the test-retest reliability and the diagnostic validity of the Coma Recovery Scale-Revised (CRS-R).

NCT ID: NCT02878837 Completed - Clinical trials for Minimally Conscious State

Dexmedetomidine vs Midazolam for Intraoperative Sedation

Start date: January 2016
Phase: Phase 4
Study type: Interventional

This randomized, open clinical trial sought to compare the use of Midazolam and Dexmedetomidine during surgery in patients under regional anesthesia. The primary objective was to determine the superiority of either drug during the intraoperative period regarding: 1- Depth of sedation and 2- incidence of complications. Secondary objectives included the determination of superiority regarding the postoperative period. For that, patients were randomized into two groups and sedated with either Midazolam or Dexmedetomidine.

NCT ID: NCT02626403 Completed - Clinical trials for Minimally Conscious State

Fronto-parietal tDCS in Severely Brain Injured Patients With Disorders of Consciousness

Start date: January 2015
Phase: N/A
Study type: Interventional

Previous studies showed that anodal transcranial direct current stimulation (tDCS) transiently improves performance of memory and attention. In severely brain injured patients with disorders of consciousness (DOC), a single stimulation over the left dorsolateral prefrontal cortex has shown to improve patients' sign of consciousness. Nevertheless, other brain areas could be stimulated in order to increase the number of responders. In this study, investigators will assess the effects of bilateral fronto-parietal tDCS on Coma Recovery Scale-Revised (CRS-R) scores in patients with DOC in a double-blind sham-controlled experimental design.

NCT ID: NCT02288533 Completed - TBI Clinical Trials

Transcranial Direct Current Stimulation Effects in Patients With Chronic Consciousness Disorders

Start date: September 2014
Phase: N/A
Study type: Interventional

Chronic consciousness disorders have high level of impact on public health and its costs.

NCT ID: NCT01820923 Completed - Clinical trials for Minimally Conscious State

Transcranial Brain Stimulation in Vegetative State Patients

Start date: July 2011
Phase: N/A
Study type: Interventional

The aim of this study is to determine whether transcranial brain stimulations, such as repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS), are effective in terms of EEG coherence and clinical changes in patients in vegetative and minimally conscious state.

NCT ID: NCT01673126 Completed - Clinical trials for Minimally Conscious State

Transcranial Direct Current Stimulation in Patients With Disorders of Consciousness

tDCS in DOC
Start date: January 2010
Phase: Phase 2
Study type: Interventional

Previous studies showed that anodal transcranial direct current stimulation (tDCS) applied to the left dorsolateral prefrontal (DLPF) cortex transiently improves performance of memory and attention. Investigator assessed the effects of left DLPF-tDCS on Coma Recovery Scale-Revised (CRS-R) scores in severely brain damaged patients with disorders of consciousness in a double-blind sham-controlled experimental design.