Mild Hypercortisolism Clinical Trial
Official title:
Glucocorticoid Receptor Blockade With Mifepristone in Patients With Mild Adrenal Hypercortisolism
The purpose of this study is to determine whether mifepristone is an effective treatment for
hyperglycemia due to mild hypercortisolism.
- To test the hypothesis that GR blockade with mifepristone will decrease the severity of
metabolic syndrome features as measured by waist circumference, lipid profile, body mass
index, blood pressure and insulin resistance, measured by HOMA-IR score.
- To test the hypothesis that GR blockade with mifepristone will improve QoL, depression
and anxiety scores, measured by validated assessments, in patients with mild
hypercortisolism.
n/a