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Shanghai Non-pharmacological Intervention for Mild Cognitive Impairment and Mild Alzheimer's Disease — SIM-2  

Mild Cognitive Impairment Clinical Trial

Official title:
Shanghai Non-pharmacological Intervention for Mild Cognitive Impairment and Mild Alzheimer's Disease: Combined Low Inflammatory-index Diet, Physical Exercises, and Cognitive Training in Nursing Home

Clinical Trial Summary

This study is a multicentre, randomized, double-blind, controlled trial that aims to investigate the efficacy of multi-domain life-style intervention including low inflammatory-index diet, exercise, and cognitive training in patients with mild cognitive impairment and mild Alzheimer's disease.

Clinical Trial Description

This is a multicentre, randomized, double-blind, controlled trial that aims to investigate the efficacy of multi-domain life-style intervention including low inflammatory-index diet, exercise, and cognitive training in patients with mild cognitive impairment and mild Alzheimer's disease. Patients who eligible to the inclusion criteria and ineligible to the exclusion criteria will be randomly assigned into three groups by a 1:1:1 ratio. Patients in first arm will receive multi-domain life-style intervention including low inflammatory-index diet, exercise, and cognitive training. Patients in the second arm will receive intervention of exercise and cognitive training. Patients in the third arm will receive regular health advice. We hypothesize that the multi-domain intervention will reduce impairment in the study group compared to the control group during the 2-year intervention period. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05887674
Study type Interventional
Source Ruijin Hospital
Contact Binyin Li, Dr
Phone 021-64370045
Email lby11917@rjh.com.cn
Status Recruiting
Phase N/A
Start date May 11, 2023
Completion date August 30, 2026
View Details
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