Mild Cognitive Impairment Clinical Trial
Official title:
Usefulness of a Home-based Cognitive Monitoring in Non-demented Patients With High-risk of Dementia: a Prospective Observational Study
This study is an observational study to confirm usefulness of a home-based cognitive monitoring in non-demented patients with high-risk of dementia
Status | Recruiting |
Enrollment | 40 |
Est. completion date | December 30, 2020 |
Est. primary completion date | November 1, 2020 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 50 Years and older |
Eligibility |
Inclusion Criteria: - persistent cognitive complaints - aged 50 years old or older - below -1.0 standard deviation in any domain of detailed neuropsychological tests battery named SNSB (Seoul neuropsychological screening battery) - no ADL (activities of daily living) limitation - subjects who agreed to participate Exclusion Criteria: - dementia patients - other structural brain disorders such as hydrocephalus, hemorrhage, or tumors - other neurological disease such as Huntington's disease, Parkinson's disease, or epilepsy |
Country | Name | City | State |
---|---|---|---|
Korea, Republic of | Uijeongbu St. Mary's hospital | Uijeongbu |
Lead Sponsor | Collaborator |
---|---|
Asan Medical Center |
Korea, Republic of,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | home-based cognitive monitoring score | a 3-5 minutes brief cognitive testing (range 0~30, higher score means better outcome) using telephone | 3 months (at baseline, 3 months from baseline, 6 months from baseline) | |
Secondary | Hippocampal atrophy grade | baseline brain MRI markers for hippocampal atrophy using Scheltens' visual rating scale (range 0~4, higher score means more hippocampal atrophy) | at baseline | |
Secondary | Number of lacunes | number of lacunes using manual counting on brain MRI (no limit) | at baseline | |
Secondary | Number of microbleeds | number of microbleeds using manual counting on brain MRI (no limit) | at baseline |
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