South Korean Study to Prevent Cognitive Impairment and Protect Brain Health Through Lifestyle Intervention — SUPERBRAIN  

Mild Cognitive Impairment Clinical Trial

Official title: A Randomized Controlled Study to Evaluate Applicability of Korean Multidomain Intervention Program in the South Korean Study to Prevent Cognitive Impairment and Protect Brain Health Through Lifestyle Intervention

Status Completed

Clinical Trial Summary

This study evaluates acceptability and efficacy of multidomain intervention program to prevent cognitive impairment and protect brain health in Korean at-risk elderly. A third of participants will receive facility-based intervention for 6 months, a third will receive home-based intervention for 6 months, and a third is waiting list controls.

Clinical Trial Description

Despite extensive research in the field of Alzheimer's disease (AD), no treatment has yet been developed to modify the progression of AD. Therefore, it is important to manage vascular and metabolic risk factors, to eat healthy foods, to exercise, and to participate in social activities to prevent dementia. The FINGER study showed that the multi-domain intervention program is effective to prevent cognitive impairment and disability in elderly.

In South Korea, exercise and leisure programs, and brain activity for the elderly also have been conducted in welfare centers and public health centers. However, there are not enough programs that have proven effective in the studies.

So the investigators would like to develop a multi-domain intervention program and investigate applicability and efficacy before a large-scale randomized controlled trial. ;

Related Conditions & MeSH terms

• Aged
• Cognitive Dysfunction
• Mild Cognitive Impairment

• NCT number: NCT03980392
• Study type: Interventional
• Source: Inha University Hospital
• Status: Completed
• Phase: N/A
• Start date: May 29, 2019
• Completion date: February 25, 2020