Mild Cognitive Impairment Clinical Trial
Official title:
Non-pharmacological Interventions on Cognitive Functions in Older People With Mild Cognitive Impairment
This project is proposed to be a three-year project. The purposes of this project are to develop and examine physical activity program, cognitive rehabilitation training, and new life-style (combination of exercise and cognitive) interventions on primary outcomes (cognitive function), and secondary outcomes (physical fitness, QOL and depression) among community-dwelling elderly adults with MCI.
Aim. develop and examine physical activity program, cognitive rehabilitation training, and
new life-style (combination of exercise and cognitive) interventions on primary outcomes
(cognitive function), and secondary outcomes (physical fitness, QOL and depression) among
community-dwelling elderly adults with MCI.
Background. Mild cognitive impairment (MCI) is a common clinical syndrome that identifies
people at high risk of developing dementia, and the prevalence range from 7.7 to 51.7%.
Although treatments for MCI are currently unavailable, preliminary evidence has identified
potential neuro-protective effects of exercise program and cognitive rehabilitation, which
may lead to improved outcomes. However, the design and delivery of an appropriate program for
people with MCI is challenging for having physical, psychological, cognitive, and social
barriers.
Design. A prospective randomized control trial. We developed a Physical activity
stage-matched intervention (SMI) (1st year), cognitive rehabilitation (2nd year) and New
lifestyle program
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