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Memory Improvement Through Nicotine Dosing (MIND) Study — MIND  

Mild Cognitive Impairment Clinical Trial

Official title:
Long-Term Nicotine Treatment of Mild Cognitive Impairment

Clinical Trial Summary

The purpose of the study is to see if daily transdermal nicotine is able to produce a significant cognitive, clinical and functional improvement in participants with MCI. Neuronal nicotinic receptors have long been known to play a critical role in memory function in preclinical studies, with nicotine improving attention, learning, and memory function. The study will enroll 380 participants for a 2 year period. Participants will be randomized (50:50) to either the transdermal nicotine, beginning at 7mg/day, and increasing to 21mg/day, or placebo skin patch.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02720445
Study type Interventional
Source University of Southern California
Contact
Status Active, not recruiting
Phase Phase 2
Start date January 13, 2017
Completion date August 2025
View Details
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