Adaptive Cognitive Training in Healthy Older Adults

Mild Cognitive Impairment Clinical Trial

Official title:

Adaptive Cognitive Training in Healthy Older Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT02205710
• Other study ID #: M16-14-018
• Status: Completed
• Phase: N/A
• Start date: August 2016
• Est. completion date: August 2018

Study information

• Verified date: August 2017
• Source: Bruyere Research Institute
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Cognitive training has emerged as a promising method to maintain, enhance, and rehabilitate cognitive function in older adults and individuals with dementia. In recent years, such training has become particularly appealing in the clinical context, with many paradigms aimed specifically at adults experiencing various stages of cognitive decline due to Mild Cognitive Impairment, Alzheimer's disease, and vascular dementias. However, basic questions remain. For example, uncertainty persists regarding factors that influence observed improvements as well as the conditions that would maximize transfer and sustainability of training effects. The objective of this study is to evaluate factors that may maximize the benefits of computerized cognitive training in older adults.

Description:

The study involves 25 sessions of an adaptive cognitive training program, completed over 5 weeks. Pre and post training assessments will evaluate any near and far transfer effects of training.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 99
• Est. completion date: August 2018
• Est. primary completion date: August 2018
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

• English as the maternal or primary spoken language.

• Good self-reported health (i.e., no cerebro-, or cardio-vascular disease or neurological disease).

• Normal or corrected-to-normal vision and hearing.

Exclusion Criteria:

• Poor hearing or vision

• Inadequate understanding of the English language

Related Conditions & MeSH terms

• Alzheimer Disease
• Alzheimer`s Disease
• Cognitive Dysfunction
• Mild Cognitive Impairment
• Mild to Moderate Dementia

Intervention

Other:
• Computerized cognitive training

• Computerized games

Locations

Country	Name	City	State
Canada	Bruyere Continuing Care	Ottawa	Ontario

Sponsors (2)

Lead Sponsor	Collaborator
Bruyere Research Institute	University of Ottawa

Country where clinical trial is conducted

Canada, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in ratings on cognitive training survey	This survey aims to assess participant perceptions on cognitive training, and includes a series of related questions, rated on a scale of 1-7.	Baseline, week 5
Primary	Change in neural activity	We will measure resting state as well as task-related EEG responses to determine the effects of cognitive training at the neural level.	Baseline, week 5
Primary	Change in performance on neuropsychological tests	Using a set of standard neuropsychological evaluations, we will measure changes in attention, memory, and executive function following cognitive training.	Baseline, week 5
Secondary	Change in ratings of psychological wellbeing	We will use standardized questionnaires to assess quality of life, in order to measure the influence of cognitive training on factors related to wellbeing.	Baseline, week 5