Mild Cognitive Impairment Clinical Trial
Official title:
Measuring the Impact of Cognitive and Psychosocial Interventions in Persons With Mild Cognitive Impairment
Memory interventions are training programs that provide a variety of cognitive and
psychological strategies meant to improve memory. These interventions have been shown to
yield significant benefits to normal aged persons and small-size studies have shown that
they are suitable and beneficial for persons with mild cognitive impairment. The goal of
this proposal is to assess with a well-controlled design the efficiency and specificity of
cognitive training in persons with mild cognitive impairment.
The hypothesis is that cognitive training can improve the cognition of persons with mild
cognitive impairment and that this improvement can be enduring.
Status | Completed |
Enrollment | 145 |
Est. completion date | January 2016 |
Est. primary completion date | January 2016 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 55 Years and older |
Eligibility |
Inclusion Criteria: - francophone - MCI identified by a doctor - normal corrected vision - good hearing Exclusion Criteria: - history of neurological disorder - major psychiatric illness - alcoholism - general anesthesia in the previous six months - significant impairment of physical mobility |
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
Country | Name | City | State |
---|---|---|---|
Canada | Centre de recherche de l'Institut universitaire de geriatrie de Montreal | Montreal | Quebec |
Canada | Centre hospitalier Robert-Giffard | Quebec |
Lead Sponsor | Collaborator |
---|---|
Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal | Laval University |
Canada,
Belleville S, Gilbert B, Fontaine F, Gagnon L, Ménard E, Gauthier S. Improvement of episodic memory in persons with mild cognitive impairment and healthy older adults: evidence from a cognitive intervention program. Dement Geriatr Cogn Disord. 2006;22(5-6):486-99. Epub 2006 Oct 16. — View Citation
Belleville S. Cognitive training for persons with mild cognitive impairment. Int Psychogeriatr. 2008 Feb;20(1):57-66. Epub 2007 Oct 25. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change in memory measures | Unrelated word list learning and Face-name memory tests | one week before and after intervention, and three and six months later | No |
Secondary | generalization of therapeutic gains to everyday life | Self-Evaluation Complaints Questionnaire, Activities of Daily Living- Prevention Instrument questionnaire, Multifactorial Memory Questionnaire tests and participants will be asked to press a button to record each occasion when they use a strategy in their daily lives. | one week before and after intervention, and three and six months later | No |
Secondary | Change in psychological health measures | geriatric anxiety inventory, griatric depression scale and general well-being schedule tests | one week before and after intervention, and 3 and 6 months later | No |
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