Mild Cognitive Impairment Clinical Trial
Official title:
The Effects of a High Fat, Low Carbohydrate or a Low Fat, High Carbohydrate Diet on Mood Cognition and Appetite
Verified date | March 2018 |
Source | University of Nottingham |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
A previous study has found that the consumption of a high fat, low carbohydrate meal results in increased feelings of calmness, friendliness and an increase in subjective energy levels in comparison to a low fat, high carbohydrate meal. The purpose of this study is to investigate whether a high fat, low carbohydrate diet for a longer duration (of 2 weeks) can enhance or sustain these changes in comparison to a low fat, high carbohydrate meal.
Status | Completed |
Enrollment | 20 |
Est. completion date | March 2013 |
Est. primary completion date | December 2012 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | Female |
Age group | 18 Years to 45 Years |
Eligibility |
Inclusion Criteria: - female - BMI 18.5-25kg/m2 - aged 18-45 years - regular breakfast eaters - regular menstrual cycle - healthy Exclusion Criteria: - Significant gastrointestinal disease, gastrointestinal surgery, diabetes or any other significant major medical morbidity - History of significant eating disorder (anorexia, bulimia) - Habitual dietary protein intake >20% of total energy intake - pregnancy or breast feeding - anaemia (Hb <11.5g/dL) - random blood glucose concentration >8mmol/l - no medication use other than contraception - significant weight loss/gain (>14lb in previous 3 months) |
Country | Name | City | State |
---|---|---|---|
United Kingdom | University of Nottingham | Nottingham | Notts |
Lead Sponsor | Collaborator |
---|---|
University of Nottingham | Mars, Inc. |
United Kingdom,
Benton D, Parker PY. Breakfast, blood glucose, and cognition. Am J Clin Nutr. 1998 Apr;67(4):772S-778S. — View Citation
Pollitt E, Mathews R. Breakfast and cognition: an integrative summary. Am J Clin Nutr. 1998 Apr;67(4):804S-813S. Review. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Clear-headedness | Subjective mood measurement, assessed using visual analogue scale, in response to a test meal | after 2 week intervention period | |
Secondary | Reaction time | cognitive function measurement, assessed using choice reaction time, in response to a test meal | after 2 week intervention |
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