Mild Cognitive Impairment (MCI) Clinical Trial
Official title:
Computer-based Sensory-cognitive and Physical Fitness Training in Mild Cognitive Impairment (MCI) and Mild Alzheimer's Disease (AD)
Age-related cognitive decline is unavoidable. However, recent results of
neuroplasticity-based research show that neuroplasticity-based training and physical
activity might have the potential to decelerate or even reverse effects of aging and
age-related cognitive impairments. Little is known whether these results also apply to
pathological processes of aging such as mild cognitive impairment (MCI) and dementia.
This multi-center study aims at investigating efficiency and feasibility of a
neuroplasticity-based auditory discrimination training and a physical fitness training for
patients suffering from mild cognitive impairment or mild Alzheimer's disease (Mini Mental
State Examination, MMSE > 19). Evaluation will include neuropsychological testing,
electroencephalography (EEG) and magnetic resonance imaging (MRI) measurements as well as
blood and liquor analyses.
n/a
Allocation: Non-Randomized, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
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