Migraine Clinical Trial
Official title:
A prospeCtive ObservatioNal Study With Acute Treatment oF rImegepant ODT on consistENcy, satisfaCtion and Tolerability of trEatment in the Real World
This study aims at characterizing the effectiveness of rimegepant as an acute migraine treatment in a real world setting on two aspects: - Consistency of response to rimegepant across multiple attacks - Effectiveness of rimegepant in users taking concomitant migraine preventive medications, namely monoclonal antibodies targeting CGRP and onabotulinumtoxinA
This study will be conducted in a real-world setting in the US using a bespoke interface contained in the Migraine Buddy mobile application. Participants who report using rimegepant for the acute treatment of migraine will be recruited and will be asked to complete a series of questionnaires during the screening and study period. Patient reported outcome measures will be collected at study enrollment, daily during the 28-day observation period, and at the end of the study period. 1. In adult patients having received a prescription for Nurtec ODT (rimegepant) for acute treatment, what is the population-level consistency of rimegepant response for pain reduction, meaningful pain relief, performance in daily activities, and return to normal function across multiple attacks in the real world, regardless of their prophylactic background? 2. In those patients, and in particular in subgroups of patients receiving migraine preventives anti-CGRP mAbs or onabotulinumtoxinA, what are the satisfaction and the tolerability of rimegepant? 3. What is the efficacy, safety, and tolerability of oral rimegepant in acute migraine treatment, when taken in combination with these preventives that act on the same pathway? ;
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