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Comparison of the Effect of Medication Therapy in Alleviating Migraine With Patent Foramen Ovale — COMPETE  

Migraine Clinical Trial

Official title:
COMParison of the EffecT of mEdication Therapy: Anticoagulation Versus Anti-platelet Versus Migraine Therapy in Alleviating Migraine With Patent Foramen Ovale

Clinical Trial Summary

Migraine attack is an episodic disorder that affects approximately 12% of the population. Previous studies have shown that 41-48% of migraineur have a combination of patent foramen ovale (PFO). Clinical observational studies have been linking medication therapies which include anticoagulation and anti-platelet therapy with the effectiveness in improving migraine symptoms and reducing the frequency of attacks in patients combined with a PFO. However, it has been unclear whether the effectiveness of anticoagulation or anti-platelet therapy outweigh the conventional migraine medication therapy, as a result, we designed a multi-center randomized clinical trial aiming to examine the effectiveness of anticoagulation versus anti-platelet versus migraine medication therapy in migraine patients with PFO and provide a clinical guidance for migraineur.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05546320
Study type Interventional
Source Chinese Academy of Medical Sciences, Fuwai Hospital
Contact Xiangbin Pan
Phone 88396666
Email panxiangbin@fuwaihospital.org
Status Recruiting
Phase Phase 4
Start date October 15, 2022
Completion date June 1, 2025
View Details
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