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Copy Number Variation in CHRNA7 Gene in Migraine and Gene Expression

Migraine Clinical Trial

Official title:
Copy Number Variation in Migraine and Gene Expression

Clinical Trial Summary

Migraine is a common and possible hereditary disease. Copy number variation (CNV) is a phenomenon in which parts of the genome are repeated and the number of repeats in the genome varies between individuals in the human population.The CHRNA7 gene has a major role in the neuropsychiatric phenotypes observed in patients. The 15q13.3 gain/loss variation in this gene may be associated with migraine.

Clinical Trial Description

Migraine is a common neurological disorder. Although they have different genetic bases according to their types, cholinergic receptors after calcium channels play an important role in the clinic and genetics of the disease. Neuronal acetylcholine receptor subunit alpha-7, also known as nAChRα7, is a protein that in humans is encoded by the CHRNA7 gene. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04912752
Study type Interventional
Source University of Gaziantep
Contact
Status Completed
Phase N/A
Start date April 5, 2020
Completion date January 2, 2021
View Details
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