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NCT04750967 Clinical Trial

Amitriptyline vs GON and SON Blocks in Migraine

Migraine Clinical Trial

Official title:
Comparison of Amitriptyline and Nerve Blocks (GON and SON) in Patients With Migraine

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT04750967
Other study ID # E-70847213-929-3410
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date April 3, 2021
Est. completion date July 15, 2023

Study information
Verified date September 2023
Source Dr. Lutfi Kirdar Kartal Training and Research Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Comparison of efficacy and safety of amitriptyline and nerve blocks

Description:

This study aims to compare the efficacy and safety of amitriptyline and nerve blocks (greater occipital nerve and supraorbital nerve)

Recruitment information / eligibility
Status Completed
Enrollment 57
Est. completion date July 15, 2023
Est. primary completion date January 1, 2022
Accepts healthy volunteers No
Gender All
Age group 18 Years to 50 Years
Eligibility Inclusion Criteria: - Diagnosed with migraine according to ICHD-3 Exclusion Criteria: - Being over 50 years or under 18 years - Malignancy and other systemic diseases

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Lidocaine 1% Injectable Solution
Repeated injections of lidocaine to greater occipital nerve and supraorbital nerve once a week for first four weeks then once a month for five months
• Amitriptyline
Amitriptyline 25 mg daily

Locations
Country Name City State
Turkey Cem Bölük Istanbul Fatih

Sponsors (1)
Lead Sponsor Collaborator
Dr. Lutfi Kirdar Kartal Training and Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome
Type Measure Description Time frame Safety issue
Primary Number of Participants with 50% Reduction of Headache Frequency Monthly headache frequency will be followed 6 months
Secondary Side effects Major and minor side effects will be followed 6 months
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