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Study to Evaluate the Efficacy and Safety of Erenumab (AMG 334) in Migraine Prevention — STRIVE  

Migraine Clinical Trial

Official title:
A Phase 3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of AMG 334 in Migraine Prevention

Clinical Trial Summary

The primary objective of the study was to evaluate the effect of erenumab compared to placebo on the change from baseline in monthly migraine days.

Clinical Trial Description

This was a multicenter, randomized, double-blind, placebo-controlled, parallel-group trial. The trial consisted of four phases: screening (≤ 3 weeks of initial screening and a 4-week baseline phase); the double-blind treatment phase (24 weeks) in which participants received placebo or erenumab 70 mg or 140 mg daily; the active-treatment phase, in which participants underwent repeat randomization and were assigned to receive 70 mg or 140 mg of erenumab (28 weeks); and a safety follow-up phase (12 weeks). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02456740
Study type Interventional
Source Amgen
Contact
Status Completed
Phase Phase 3
Start date July 17, 2015
Completion date June 19, 2017
View Details
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