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Migraine With Aura clinical trials

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NCT ID: NCT00449540 Completed - Migraine With Aura Clinical Trials

Efficacy and Safety of TMS for the Preemptive Treatment of Migraine With Aura

Start date: August 2006
Phase: Phase 3
Study type: Interventional

Assess safety and efficacy of Transcranial Magnetic Stimulation (TMS) for the treatment of migraine with aura The hypothesis is that TMS treatments delivered to the occipital cortex of the brain can stop or interrupt the spreading cortical brain activity that causes or contributes to the migraine headache. Two TMS treatments at an intensity of <1 Tesla for ~500 microseconds, approximately 30 seconds apart, may stop the aura and prevent the subsequent headache.

NCT ID: NCT00358839 Completed - Clinical trials for Familial Hemiplegic Migraine

Calcitonin Gene Related Peptide-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2.

Start date: July 2006
Phase: N/A
Study type: Interventional

The aim of the present study is to explore functional consequences of migraine gene mutations on their responses to Calcitonin Gene Related Peptide (CGRP)infusion.

NCT ID: NCT00334178 Completed - Clinical trials for Migraine Without Aura

Evaluation of the Efficacy and Safety of Laxymig® as Prophylactic Treatment in Patients With Migraine

Start date: November 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of Laxymig® ER compared with placebo in prophylactic monotherapy treatment of migraine headache.

NCT ID: NCT00332007 Completed - Migraine With Aura Clinical Trials

Tonabersat in the Prophylaxis of Migraine With Aura

Start date: May 2006
Phase: Phase 2
Study type: Interventional

Overall trial objectives: 1. Can treatment with tonabersat reduce the number of days with aura and/or migraine headache in patients with migraine with aura 2. How well tolerated is treatment with tonabersat The study is based on the hypothesis that the unique mechanism of action of tonabersat will inhibit some of the early events in the generation of aura and migraine headache and so be effective as prophylactic treatment

NCT ID: NCT00311662 Completed - Clinical trials for Migraine Without Aura

Efficacy and Tolerability of Tonabersat in the Prophylaxis of Migraine Headache

Start date: April 2006
Phase: Phase 2
Study type: Interventional

Overall trial objectives: - Can treatment with tonabersat reduce the number of days with a migraine headache in patients who suffer from frequent migraine attacks - How well tolerated is treatment with tonabersat The study is based on the hypothesis that the unique mechanism of action of tonabersat will inhibit some of the early events in the generation of migraine and so be effective as prophylactic treatment

NCT ID: NCT00285402 Active, not recruiting - Migraine Clinical Trials

Efficacy and Safety Clinical Trial of Intranasal AST-726 for the Prevention of Migraine

Start date: May 2007
Phase: Phase 2
Study type: Interventional

The purpose of this migraine prevention study is to evaluate the efficacy and safety of AST-726 in moderate to severe migraine patients at one of two doses compared to placebo and compared to a baseline period as measured by a reduction in the number of migraine days.

NCT ID: NCT00257985 Completed - Healthy Volunteers Clinical Trials

Glyceryl-Trinitrate-Induced Headache in Patients With Familial Hemiplegic Migraine Type 1 and 2

Start date: April 2005
Phase: N/A
Study type: Interventional

The aim of the present study is to explore functional consequences of migraine gene mutations on their responses to GTN infusion.

NCT ID: NCT00236561 Completed - Migraine Clinical Trials

A Study of the Efficacy and Safety of Two Doses of Topiramate Compared to Placebo and Propranolol in the Prevention of Migraine

Start date: April 2001
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of two doses of topiramate (100 and 200 mg daily) versus placebo and propranolol in the prevention of migraine. The study will also assess dose response relationship of topiramate, estimate the relative efficacy of topiramate versus propranolol in prevention of migraine, and evaluate the effect of migraine prevention with topiramate versus placebo on Health Related Quality of Life.

NCT ID: NCT00236509 Completed - Migraine Clinical Trials

A Study of the Efficacy and Safety of Topiramate in the Prevention of Migraine

Start date: February 2001
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of three doses of topiramate (50 milligrams[mg], 100mg, and 200mg taken daily) compared with placebo in the prevention of migraine.

NCT ID: NCT00231595 Completed - Migraine Clinical Trials

A Study of the Efficacy and Safety of Topiramate in the Prevention of Migraine

Start date: March 2001
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of three doses of topiramate (50 milligrams[mg], 100mg, and 200mg per day) compared with placebo in the prevention of migraine. The study will also assess the dose response relationship and the efficacy of treatment with topiramate versus placebo on Health-Related Quality of Life.