Cefaliv® Compared to Neosaldina® in the Treatment of Migraine Attacks

Status Withdrawn

Clinical Trial Summary

This study evaluates the non-inferiority of Cefaliv® compared to Neosaldina® in the treatment of migraine attack in two hundred and sixteen adults of both sexes with age between eighteen and sixty five years old. The first Half of participants will receive Cefaliv®, the other half will receive Neosaldina®.

Clinical Trial Description

Cefaliv® is a combination of 3 drugs: dihydroergotamine mesylate, dipyrone sodium, and caffeine. The dihydroergotamine mesylate interacts with the serotonergic, dopaminergic and noradrenergic receptors, but it's mechanism is not totally known. The dipyrone is a non-steroidal antiinflammatory which has an analgesic, antiinflammatory and antipyretic effect. And the caffeine presents mechanisms that are not totally clear, but it may relieves the pain by activating of the central noradenosine pathway (pain suppressing system). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02706015
Study type	Interventional
Source	Ache Laboratorios Farmaceuticos S.A.
Contact
Status	Withdrawn
Phase	Phase 3
Start date	October 2020
Completion date	July 2021

View Details

See also
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