Impact of CES1 Genotype on Remimazolam

Status Recruiting

Clinical Trial Summary

Remimazolam is primarily metabolized via CES1, and other drugs that are commonly metabolized by CES1 are known to have their pharmacokinetics and clinical effects affected by genetic polymorphisms in CES1. The goal of this observational study is to investigate the impact of the CES1 genotype on the pharmacokinetics, safety, and efficacy of remimazolam in patients undergoing elective surgery.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05841667
Study type	Observational
Source	Korea University Guro Hospital
Contact	Byung Gun Lim, MD, PhD
Phone	82-2-2626-1437
Email	bglim9205@korea.ac.kr
Status	Recruiting
Phase
Start date	September 6, 2023
Completion date	December 31, 2024

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT06320626` - Pharmacokinetic-guided Dosing of Emicizumab	Phase 4
Completed	`NCT06355817` - Distraction Techniques in Periocular Anesthesia: Tapping vs Vibration	N/A
Not yet recruiting	`NCT01209481` - Impact of Educational Group Intervention on the Consumption of Fruit and Vegetables	N/A
Terminated	`NCT01570465` - Prospective Study on Severe Infections on Acute Myeloid Leukemia (AML) Patients
Completed	`NCT04169646` - Prevention and Intervention of Neck Pain in Swiss Office-Workers	N/A
Not yet recruiting	`NCT01943565` - Intrathecal Hydromorphone for Post-cesarean Delivery Pain - a Dose Finding Study	Phase 4
Completed	`NCT00519298` - Study Evaluating Effects of SAM-531 on Sleep Electroencephalogram (EEG) and Quantitative Wake EEG in Healthy Subjects	Phase 1
Completed	`NCT03541837` - Erector Spinae Plane Block and Pain Management in Cardiac Surgery	N/A
Active, not recruiting	`NCT00809575` - Quality of Life and Symptoms in Patients With Newly Diagnosed Myelodysplastic Syndromes
Completed	`NCT06383117` - Understanding Effects of Calcium on the Gut-Bone Axis	N/A
Completed	`NCT05012046` - Effect of 100% Orange Juice on Food Intake and Glycemic Response in Adults	N/A
Completed	`NCT05597969` - The Effect of an Application-based Health Intervention (FoodCoach) on Food Purchases in Switzerland	N/A
Terminated	`NCT01817153` - Effect of Hydrocortison on Post-ischemic Flow-mediated Dilation and on Thenar Oxygen Saturation in Human Septic Shock.	Phase 2/Phase 3
Not yet recruiting	`NCT05123352` - Investigation of the Gut Microbiota in Acute Myeloid Leukemia Receiving Two Different Induction Therapies
Not yet recruiting	`NCT03728114` - Effects of RIC on Cognitive Function and Blood Oxygen Levels in Unacclimatized Adult at High Altitude	N/A
Completed	`NCT01162863` - Effects of Lubiprostone on Gastrointestinal Transit & pH in Irritable Bowel Syndrome (IBS) With Constipation	N/A
Completed	`NCT05570435` - Efficacy of Milk Product Supplemented With Bioactives in Lowering Post Meal Glucose Response	N/A
Recruiting	`NCT03713931` - PUMA Implementation 2
Completed	`NCT04443231` - Prospective Clinical Study of Retinal Microvascular Alteration After ICL Implantation
Completed	`NCT05852340` - A Study to Assess Two Forms of The Study Medicine (Ritlecitinib) in Healthy Adult Participants	Phase 1