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Pilot Study of Short-Course Glucocorticoids and Rituximab for Treatment of ANCA-Associated Vasculitis — SCOUT  

Microscopic Polyangiitis Clinical Trial

Official title:
Short-Course Glucocorticoids and Rituximab in ANCA-Associated Vasculitis

Clinical Trial Summary

The purpose of this pilot study is to test whether an 8-week course of glucocorticoids, combined with rituximab, is effective in treating ANCA-associated vasculitis.

Clinical Trial Description

The primary aim of this pilot study is to examine whether an 8 week course of glucocorticoids, in combination with rituximab, is effective in inducing and maintaining disease remission for up to 6 months in a subset of patients with ANCA-associated vasculitis (AAV) who have a more favorable prognosis. This pilot study will enroll 20 patients with active AAV. Close patient follow-up will insure that any patients who require courses of glucocorticoids longer than two months will receive longer therapy, if appropriate for their well-being. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02169219
Study type Interventional
Source Massachusetts General Hospital
Contact
Status Completed
Phase Phase 4
Start date June 2014
Completion date November 1, 2017
View Details
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