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Microsatellite Stable clinical trials

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NCT ID: NCT04194359 Active, not recruiting - Clinical trials for Metastatic Colorectal Cancer

Sintilimab (IBI308) Combined With Bevacizumab + XELOX Regimen in Metastatic Colorectal Cancer

Start date: February 4, 2021
Phase: Phase 2
Study type: Interventional

A phase II clinical study of Sintilimab (IBI308) combined with Bevacizumab, Oxaliplatin and Capecitabine regimen as first-line treatment in patients with RAS-mutant and microsatellite stable metastatic colorectal cancer. A total of 25 patients are planned to be enrolled.

NCT ID: NCT03983993 Active, not recruiting - Clinical trials for Stage IV Colorectal Cancer AJCC v8

Niraparib and Panitumumab in Patients With Advanced or Metastatic Colorectal Cancer

NIPAVect
Start date: October 15, 2019
Phase: Phase 2
Study type: Interventional

This phase II trial studies the side effects and how well niraparib and panitumumab work in treating patients with colorectal cancer that has spread to other places in the body. Niraparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Immunotherapy with monoclonal antibodies, such as panitumumab, may help the body's immune system attack the cancer and may interfere with the ability of tumor cells to grow and spread. Giving niraparib and panitumumab may work better in treating patients with colorectal cancer.