Clinical Trials Logo

Clinical Trial Summary

To establish if, in patients with new diagnosis of left ventricular dilatation without documentation at the coronary artery angiography of significant coronary artery lesions, there is a damage of the coronary microcirculation at the IMR (index of microcirculatory resistance) assessment


Clinical Trial Description

The Authors will enroll at the moment of coronary artery angiography patients without history of ischemic heart disease and new diagnosis (at transthoracic echocardiography) of left ventricular dilation.

All patients will undergo coronary artery angiography. To be enrolled, it is necessary to have the absence of significant coronary artery stenosis (angiographic evaluation of the lesion >40%) in all the vessels (main and side branch).

The Authors will proceed to perform the evaluation of the index of microvascular resistance (IMR). The target vessel will be the left anterior descending artery.

An intracoronary pressure/temperature sensor-tipped guidewire will be used. Thermodilution curves will be obtained during maximal hyperemia. The IMR will be calculated from the ratio of the mean distal coronary pressure at maximal hyperemia to the inverse of mean hyperemic transit time. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT02705170
Study type Observational
Source University Hospital of Ferrara
Contact
Status Completed
Phase
Start date March 2016
Completion date April 30, 2018

See also
  Status Clinical Trial Phase
Active, not recruiting NCT05428787 - Resynchronization in Patients With HF in AF Trial Undergoing Pace & AVNA Strategy With LBBAP Compared With BiV Pacing N/A
Not yet recruiting NCT05567445 - Outcome of Cardiomyopathic Adults Admission in ICU.
Completed NCT02555527 - Contrast Echocardiography Cost Effectiveness for Left Ventricular Thrombus Assessment N/A
Completed NCT00371891 - Ontario Multidetector Computed Tomographic (MDCT) Coronary Angiography Study (OMCAS) Phase 4
Recruiting NCT05552521 - Diastolic Dysfunction in Septic Shock and Cardiomyopathy Genetic Variants
Recruiting NCT04166331 - Adjunctive DobutAmine in sePtic Cardiomyopathy With Tissue Hypoperfusion Phase 3
Terminated NCT06331507 - Refinement and Assessment of New MRI Technologies for Cardiovascular Exams Using the Phillips CMR Patch N/A
Completed NCT01953523 - Safety and Clinical Outcomes Study: SVF Deployment for Orthopedic, Neurologic, Urologic, and Cardio-pulmonary Conditions N/A
Recruiting NCT04695119 - Sepsis in the ICU-II
Completed NCT03228966 - Ped HIV - Echo Study: Kenya
Not yet recruiting NCT06348732 - Diagnostic and Prognostic Role of Troponin and Brain Natriuretic Peptide in Pediatric Patients With Cardiomyopathy in Correlation to Echocardiography Findings
Recruiting NCT05556369 - Genetic Characterization of Cardiomyopathies (POLICARDIOMIO2021)
Recruiting NCT04520646 - A Pilot Study of Empagliflozin in the Treatment of Acromegalic Cardiomyopathy N/A
Not yet recruiting NCT03899298 - Safety and Clinical Outcomes With Amniotic and Umbilical Cord Tissue Therapy for Numerous Medical Conditions Phase 1
Completed NCT04323852 - Can Vitamin D Reduce Heart Muscle Damage After Bypass Surgery? Phase 4
Completed NCT03527381 - Nitric Oxide in Cardiopulmonary Bypass for Renal Protection in Cardiac Surgery Phase 1/Phase 2
Withdrawn NCT02462213 - Prospective Identification of Cardiac Amyloidosis by Cardiac Magnetic Resonance Imaging N/A
Active, not recruiting NCT00418041 - Chronic Heart Failure Analysis and Registry in the Tohoku District 2 (CHART-2 Study) N/A
Not yet recruiting NCT06091475 - Therapy to Maintain Remission in Dilated Cardiomyopathy N/A
Recruiting NCT03317964 - Genetic Basis of Pacing-induced Cardiomyopathy