Effectiveness of Ophthalmic Antiseptic Preparations

Status Completed

Clinical Trial Summary

The aim of this clinical trial is to evaluate the effectiveness of two topical antiseptics, povidone-iodine (PVI) and chlorhexidine (CHX), in reducing conjunctival bacterial flora.

Clinical Trial Description

70 patients undergoing cataract surgery were enrolled and randomly divided in two arms: 35 patients used PVI 0.66% 4 times daily starting 3 days before surgery; 35 patients used CHX 0.02% with the same posology. The contralateral eye was considered as control. Conjunctival swabs were collected in both eyes at the baseline (T0) and after three days of treatment (T1) all before cataract surgery. Conjunctival bacterial load has been evaluated through a molecular based method at T0 and T1 and compared to the control eye. ;

Study Design

Related Conditions & MeSH terms

Microbiota

Clinical Trial Details

NCT number	NCT05974124
Study type	Interventional
Source	Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Contact
Status	Completed
Phase	N/A
Start date	November 9, 2022
Completion date	February 3, 2023

View Details

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