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Exercise in Methamphetamine Use Disorder Upregulation and Neural Function

Methamphetamine Abuse Clinical Trial

Official title:
Exercise in Methamphetamine Use Disorder: Dopamine Receptor Upregulation and Neural Function

Clinical Trial Summary

The purpose of this research study is to determine the effects of an exercise intervention and health-education program on brain dopamine receptors and on cognitive functions that have been linked to these receptors.

Clinical Trial Description

After completing baseline assessments within 2 wks after admission, participants will be randomized to one of two interventions: Exercise (EX, active intervention), consisting of 3x-weekly 50-min aerobic + resistance-training sessions for 8 wk; Health Education (control intervention, CON), consisting of 50-min health education sessions 3x-weekly for 8 wk. Participants will undergo positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) scans while performing the stop signal task (SST) and the reversal learning task (RLT) (cognitive computer tasks) at baseline and after completing the 8-wk protocol. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03709667
Study type Interventional
Source University of California, Los Angeles
Contact
Status Completed
Phase Early Phase 1
Start date June 26, 2019
Completion date August 30, 2023
View Details
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