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Clinical Trial Summary

Selumetinib therapy in patients with metastatic uveal melanoma.


Clinical Trial Description

A randomised double-blind study to assess the efficacy of selumetinib (AZD6244, Hyd-Sulfate) in combination with Dacarbazine compared with placebo in combination with Dacarbazine as first systemic therapy in patients with metastatic uveal melanoma (SUMIT) ;


Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Treatment


Related Conditions & MeSH terms


NCT number NCT01974752
Study type Interventional
Source AstraZeneca
Contact
Status Completed
Phase Phase 3
Start date April 2014
Completion date October 2016

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