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A Phase II Study of Nivolumab in Patients With Genetic Alterations in DNA Damage Repair and Response Who Progressed After Standard Treatment for Metastatic Solid Cancers

Metastatic Solid Tumor Clinical Trial

Official title:
A Phase II Study of Nivolumab in Patients With Genetic Alterations in DNA Damage Repair and Response Who Progressed After Standard Treatment for Metastatic Solid Cancers

Clinical Trial Summary

A Phase II Study of Nivolumab in Patients with Genetic alterations in DNA Damage repair and response Who Progressed after Standard treatment for Metastatic Solid Cancers

Clinical Trial Description

All the patients will be included in the final analysis, with a total of 48 patients to be enrolled. Treatment will occur until disease progression, unacceptable toxicity or patient withdrawal. Study treatment consists of nivolumab 3mg/kg, and will be repeated every 2 weeks. Response evaluation will be performed every 6 weeks (+/- 1 week window period is allowed). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04761744
Study type Interventional
Source Korean Cancer Study Group
Contact Kyong Hwa Park, MD, PhD
Phone +821047617651
Email khpark@korea.ac.kr
Status Recruiting
Phase Phase 2
Start date June 14, 2019
Completion date December 2021
View Details
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