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Clinical Trial Summary

The hypothesis of this study is that the response rate of soft tissue sarcoma will be improved with the addition of PD-1 and CTLA-4 inhibition to cabozantinib, and that cabozantinib priming will increase the response to nivolumab and ipilimumab.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04551430
Study type Interventional
Source Washington University School of Medicine
Contact
Status Active, not recruiting
Phase Phase 2
Start date January 5, 2021
Completion date June 1, 2030

See also
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Completed NCT03022448 - Geriatric Assessmen of Elderly "Unsuited" Patients Receiving Trabectedin in First Line Treatment For Advanced Soft Tissue Sarcomas (STS)
Terminated NCT05100628 - A Study of NOX66 Plus Doxorubicin in Anthracycline-naïve, Adult Patients With Soft Tissue Sarcoma Phase 1
Recruiting NCT05180695 - HDM201 and Pazopanib in Patients With P53 Wild-type Advanced/Metastatic Soft Tissue Sarcomas Phase 1/Phase 2