Metastatic Renal Cell Carcinoma Clinical Trial
Official title:
A Randomized Phase II Trial of IL-2/IFN-α Plus Bevacizumab Versus IL-2/IFN-α in Metastatic Renal Cell Carcinoma (mRCC) - Danish Renal Cancer Group (DARENCA) Study-1
The purpose of this study is to determine whether interleukin-2, interferon-alpha in combination with bevacizumab are effective in the treatment of metastatic renal cell carcinoma (mRCC).
Bevacizumab as monotherapy has effect in metastatic renal cell carcinoma (mRCC). Bevacizumab
in combination with interferon-alfa (IFN-α) has significant efficacy in mRCC and has been
approved by EMA and FDA.
The present study will assess whether the combination of Interleukin-2 (IL-2) and IFN-α with
bevacizumab may add efficacy in patients with mRCC with a tolerable safety profile.
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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