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NCT01233557 Clinical Trial

Biomarkers of Bone Resorption in Metastatic Prostate Cancer

Metastatic Prostate Cancer Clinical Trial

Official title:
Measurement of Biomarkers of Bone Resorption in Patients With Hormone Sensitive Bone Metastases From Prostate Cancer Treated With Antiandrogen Therapy and Bisphosphonates

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01233557
Other study ID # 10/S0802/36
Secondary ID
Status Completed
Phase N/A
First received November 2, 2010
Last updated November 4, 2015
Start date September 2010
Est. completion date August 2014

Study information
Verified date November 2015
Source University of Aberdeen
Contact n/a
Is FDA regulated No
Health authority United Kingdom: Research Ethics Committee
Study type Observational

Clinical Trial Summary

Biomarkers of bone resorption will be measured in the blood of patients with bone metastases from prostate cancer during the course of their illness. Changes in these biomarkers will be correlated with the patient's treatment with antiandrogen therapy and bisphosphonates and the response and/or progression of their cancer. It is hoped that serial measurement of these biomarkers may allow therapeutic monitoring in the future with successful individualisation of bisphosphonate therapy for metastatic prostate cancer.

Recruitment information / eligibility
Status Completed
Enrollment 40
Est. completion date August 2014
Est. primary completion date August 2014
Accepts healthy volunteers No
Gender Male
Age group 40 Years to 80 Years
Eligibility Inclusion Criteria:

- prostate cancer with bone metastases

- hormone sensitive

Exclusion Criteria:

- inadequate renal function

- ongoing dental problems

- previous bisphosphonate therapy

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
United Kingdom Aberdeen Royal Infirmary Aberdeen

Sponsors (1)
Lead Sponsor Collaborator
University of Aberdeen

Country where clinical trial is conducted

United Kingdom, 

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